One-year post-hospital medical costs and relapse rates of bipolar disorder patients in Taiwan

A population-based study

Chao Hsiun Tang, Ming H. Hsieh, Sheng Tzu Hung, I-Hui Lee, Yung Jung Lin, Yen-Kuang Yang

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Objectives: We examined a nationwide population-based dataset of patients with bipolar disorder (BD) hospitalized in Taiwan, with our analyses focusing on one-year medical costs and relapse rates.Methods: The data for this study, covering the years 2006 and 2007, were obtained from the Taiwan National Health Insurance (NHI) claims database. The study sample comprised BD patients who were discharged from hospitals between January 1 and December 31, 2006. Annual medical costs and relapse rates were described; the Kaplan-Meier method and the generalized linear models were carried out to examine the risk factors associated with cases of relapse.Results: The annual medical costs associated with relapses among the study sample were found to be approximately 7.6 times the average per-capita NHI expenditure in Taiwan in 2006 (US$4,354 versus US$574), with a one-year relapse rate of 55%. Those patients between 20 and 60 years old with a medication possession ratio of <80 and with depressive episodes during the recruitment period were identified as being at risk of relapse.Conclusion: Bipolar disorder, which is a very costly disease, is associated with both poor medication adherence rates and frequent recurrences. Targeting drug adherence issues during maintenance treatment may well provide a valuable opportunity to reduce the risk of such recurrences.

Original languageEnglish
Pages (from-to)859-865
Number of pages7
JournalBipolar Disorders
Volume12
Issue number8
DOIs
Publication statusPublished - 2010 Dec 1

Fingerprint

Hospital Costs
Taiwan
Bipolar Disorder
Recurrence
Population
National Health Programs
Costs and Cost Analysis
Medication Adherence
Drug Delivery Systems
Health Expenditures
Linear Models
Databases

All Science Journal Classification (ASJC) codes

  • Psychiatry and Mental health
  • Biological Psychiatry

Cite this

Tang, Chao Hsiun ; Hsieh, Ming H. ; Hung, Sheng Tzu ; Lee, I-Hui ; Lin, Yung Jung ; Yang, Yen-Kuang. / One-year post-hospital medical costs and relapse rates of bipolar disorder patients in Taiwan : A population-based study. In: Bipolar Disorders. 2010 ; Vol. 12, No. 8. pp. 859-865.
@article{5abc35014e374e18b88912be7cf94bb1,
title = "One-year post-hospital medical costs and relapse rates of bipolar disorder patients in Taiwan: A population-based study",
abstract = "Objectives: We examined a nationwide population-based dataset of patients with bipolar disorder (BD) hospitalized in Taiwan, with our analyses focusing on one-year medical costs and relapse rates.Methods: The data for this study, covering the years 2006 and 2007, were obtained from the Taiwan National Health Insurance (NHI) claims database. The study sample comprised BD patients who were discharged from hospitals between January 1 and December 31, 2006. Annual medical costs and relapse rates were described; the Kaplan-Meier method and the generalized linear models were carried out to examine the risk factors associated with cases of relapse.Results: The annual medical costs associated with relapses among the study sample were found to be approximately 7.6 times the average per-capita NHI expenditure in Taiwan in 2006 (US$4,354 versus US$574), with a one-year relapse rate of 55{\%}. Those patients between 20 and 60 years old with a medication possession ratio of <80 and with depressive episodes during the recruitment period were identified as being at risk of relapse.Conclusion: Bipolar disorder, which is a very costly disease, is associated with both poor medication adherence rates and frequent recurrences. Targeting drug adherence issues during maintenance treatment may well provide a valuable opportunity to reduce the risk of such recurrences.",
author = "Tang, {Chao Hsiun} and Hsieh, {Ming H.} and Hung, {Sheng Tzu} and I-Hui Lee and Lin, {Yung Jung} and Yen-Kuang Yang",
year = "2010",
month = "12",
day = "1",
doi = "10.1111/j.1399-5618.2010.00878.x",
language = "English",
volume = "12",
pages = "859--865",
journal = "Bipolar Disorders",
issn = "1398-5647",
publisher = "Blackwell Munksgaard",
number = "8",

}

One-year post-hospital medical costs and relapse rates of bipolar disorder patients in Taiwan : A population-based study. / Tang, Chao Hsiun; Hsieh, Ming H.; Hung, Sheng Tzu; Lee, I-Hui; Lin, Yung Jung; Yang, Yen-Kuang.

In: Bipolar Disorders, Vol. 12, No. 8, 01.12.2010, p. 859-865.

Research output: Contribution to journalArticle

TY - JOUR

T1 - One-year post-hospital medical costs and relapse rates of bipolar disorder patients in Taiwan

T2 - A population-based study

AU - Tang, Chao Hsiun

AU - Hsieh, Ming H.

AU - Hung, Sheng Tzu

AU - Lee, I-Hui

AU - Lin, Yung Jung

AU - Yang, Yen-Kuang

PY - 2010/12/1

Y1 - 2010/12/1

N2 - Objectives: We examined a nationwide population-based dataset of patients with bipolar disorder (BD) hospitalized in Taiwan, with our analyses focusing on one-year medical costs and relapse rates.Methods: The data for this study, covering the years 2006 and 2007, were obtained from the Taiwan National Health Insurance (NHI) claims database. The study sample comprised BD patients who were discharged from hospitals between January 1 and December 31, 2006. Annual medical costs and relapse rates were described; the Kaplan-Meier method and the generalized linear models were carried out to examine the risk factors associated with cases of relapse.Results: The annual medical costs associated with relapses among the study sample were found to be approximately 7.6 times the average per-capita NHI expenditure in Taiwan in 2006 (US$4,354 versus US$574), with a one-year relapse rate of 55%. Those patients between 20 and 60 years old with a medication possession ratio of <80 and with depressive episodes during the recruitment period were identified as being at risk of relapse.Conclusion: Bipolar disorder, which is a very costly disease, is associated with both poor medication adherence rates and frequent recurrences. Targeting drug adherence issues during maintenance treatment may well provide a valuable opportunity to reduce the risk of such recurrences.

AB - Objectives: We examined a nationwide population-based dataset of patients with bipolar disorder (BD) hospitalized in Taiwan, with our analyses focusing on one-year medical costs and relapse rates.Methods: The data for this study, covering the years 2006 and 2007, were obtained from the Taiwan National Health Insurance (NHI) claims database. The study sample comprised BD patients who were discharged from hospitals between January 1 and December 31, 2006. Annual medical costs and relapse rates were described; the Kaplan-Meier method and the generalized linear models were carried out to examine the risk factors associated with cases of relapse.Results: The annual medical costs associated with relapses among the study sample were found to be approximately 7.6 times the average per-capita NHI expenditure in Taiwan in 2006 (US$4,354 versus US$574), with a one-year relapse rate of 55%. Those patients between 20 and 60 years old with a medication possession ratio of <80 and with depressive episodes during the recruitment period were identified as being at risk of relapse.Conclusion: Bipolar disorder, which is a very costly disease, is associated with both poor medication adherence rates and frequent recurrences. Targeting drug adherence issues during maintenance treatment may well provide a valuable opportunity to reduce the risk of such recurrences.

UR - http://www.scopus.com/inward/record.url?scp=78650556146&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=78650556146&partnerID=8YFLogxK

U2 - 10.1111/j.1399-5618.2010.00878.x

DO - 10.1111/j.1399-5618.2010.00878.x

M3 - Article

VL - 12

SP - 859

EP - 865

JO - Bipolar Disorders

JF - Bipolar Disorders

SN - 1398-5647

IS - 8

ER -