Optical detection of glucose concentration in samples with scattering particles

Li Han Lin, Yu Lung Lo, Chia Chi Liao, Jian Xiang Lin

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)


An optical-based method is proposed for measuring the glucose concentration of samples containing scattering particles. In the proposed approach, a Stokes-Mueller reflection-based polarimetry technique is used to solve the Mueller matrices of a turbid glucose sample with circular birefringence and depolarization properties given six incident lights with different polarization states. Using an error function defined as the difference between the simulated output Stokes vectors and the experimental ones, a genetic algorithm is used to inversely derive the optical rotation and depolarization parameters of the experimental sample corresponding to the glucose concentration and scattering depolarization effect, respectively. The validity of the proposed method is demonstrated using glucose samples containing 0.02 ml and 0.04 ml lipofundin, respectively.

Original languageEnglish
Pages (from-to)10425-10431
Number of pages7
JournalApplied optics
Issue number35
Publication statusPublished - 2015 Dec 10

All Science Journal Classification (ASJC) codes

  • Atomic and Molecular Physics, and Optics
  • Engineering (miscellaneous)
  • Electrical and Electronic Engineering


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