Optimal adaptive control schemes for PHB production in fed-batch fermentation of Ralstonia eutropha

Wei Wu, Song Yi Lai, Ming Feng Jang, Yi Shyong Chou

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)

Abstract

A dynamic model for a fed-batch fermentation of Ralstonia eutropha for PHB production is presented. Based on the simplified kinetics, some of kinetic parameters are very sensitive to uncertainties. To develop the robust and feasible feeding strategy, the specific optimal adaptive control strategy is determined by solving the constrained discrete-time optimization algorithm using the genetic algorithm solver in Matlab. The proposed control methods are implemented to the feed flow manipulation with stepwise changes. Through Lyapunov stability analysis, the closed-loop stability regarding the state estimation errors and parametric uncertainties is investigated. Finally, simulations show that the satisfactory output tracking performance is achieved under the two-input control configuration.

Original languageEnglish
Pages (from-to)1159-1168
Number of pages10
JournalJournal of Process Control
Volume23
Issue number8
DOIs
Publication statusPublished - 2013 Aug 19

All Science Journal Classification (ASJC) codes

  • Control and Systems Engineering
  • Modelling and Simulation
  • Computer Science Applications
  • Industrial and Manufacturing Engineering

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