Abstract
Oxidative free radical reactions between 2-benzyl-1,4-naphthoquinones and β-dicarbonyl compounds are described. Electrophilic carbon-centered radicals produced by the manganese(III) acetate or cerium(IV) ammonium nitrate oxidation of β-dicarbonyl compounds undergo efficient addition to a C-C double bond of quinone ring. This free radical reaction provides a novel method for the synthesis of naphthacene-5,12-diones.
Original language | English |
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Pages (from-to) | 7829-7837 |
Number of pages | 9 |
Journal | Tetrahedron |
Volume | 57 |
Issue number | 37 |
DOIs | |
Publication status | Published - 2001 Sep 10 |
All Science Journal Classification (ASJC) codes
- Biochemistry
- Drug Discovery
- Organic Chemistry