Palladium-catalyzed dehalogenation of 5-halopyrazoles

Chun-Yen Chen, Yu Ying Huang, Wei Nien Su, Kimiyoshi Kaneko, Masayuki Kimura, Hiroyuki Takayama, Fung Fuh Wong

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

A new and efficient method for the dehalogenation of 5-halopyrazoles was developed by using the catalytic amount of palladium (II) chloride and triphenylphosphine as a ligand at reflux under constant flow of hydrogen gas. The reaction gave the corresponding pyrazole products in good to excellent yields (≥83%)..

Original languageEnglish
Pages (from-to)183-189
Number of pages7
JournalJournal of Heterocyclic Chemistry
Volume49
Issue number1
DOIs
Publication statusPublished - 2012 Jan 1
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

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