Papillary cystic tumor of the pancreas

A case indistinguishable from oncocytic carcinoma

Wen Ying Lee, Ching Cherng Tzeng, Ying Tai Jin, Nan-Haw Chow, Chi Man Yip, Jenq-Chang Lee

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

A case of papillary cystic tumor (PCT) of the pancreas in a 55-year-old woman is described. She presented with a gradually enlarging and painless abdominal mass for >26 years. The tumor was encapsulated and measured 16 × 12 × 10 cm. The gross features and conventional light microscopic appearances of this tumor were consistent with the previously reported cases of PCT. Perineural and capsular invasions were found. In addition to the densely packed blue granules in the cytoplasm demonstrated by phosphotungstic acid-hematoxylin stain, ultrastructural study revealed the tumor cells to be packed with numerous mitochondria. These oncocytes comprised almost all the non-necrotic tumor areas. Therefore, this case was indistinguishable pathologically from oncocytic carcinoma of the pancreas. DNA flow cytometry showed a diploid pattern and low S phase fraction, indicating that the tumor has a low proliferative activity and a favorable prognosis.

Original languageEnglish
Pages (from-to)127-132
Number of pages6
JournalPancreas
Volume8
Issue number1
DOIs
Publication statusPublished - 1993 Jan 1

Fingerprint

Pancreas
Carcinoma
Neoplasms
Phosphotungstic Acid
Oxyphil Cells
Hematoxylin
Diploidy
S Phase
Flow Cytometry
Mitochondria
Cytoplasm
Coloring Agents
Light
DNA

All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Hepatology
  • Endocrinology

Cite this

Lee, Wen Ying ; Tzeng, Ching Cherng ; Jin, Ying Tai ; Chow, Nan-Haw ; Yip, Chi Man ; Lee, Jenq-Chang. / Papillary cystic tumor of the pancreas : A case indistinguishable from oncocytic carcinoma. In: Pancreas. 1993 ; Vol. 8, No. 1. pp. 127-132.
@article{bc99c51a05cc4e808c8fdc0e311f6223,
title = "Papillary cystic tumor of the pancreas: A case indistinguishable from oncocytic carcinoma",
abstract = "A case of papillary cystic tumor (PCT) of the pancreas in a 55-year-old woman is described. She presented with a gradually enlarging and painless abdominal mass for >26 years. The tumor was encapsulated and measured 16 × 12 × 10 cm. The gross features and conventional light microscopic appearances of this tumor were consistent with the previously reported cases of PCT. Perineural and capsular invasions were found. In addition to the densely packed blue granules in the cytoplasm demonstrated by phosphotungstic acid-hematoxylin stain, ultrastructural study revealed the tumor cells to be packed with numerous mitochondria. These oncocytes comprised almost all the non-necrotic tumor areas. Therefore, this case was indistinguishable pathologically from oncocytic carcinoma of the pancreas. DNA flow cytometry showed a diploid pattern and low S phase fraction, indicating that the tumor has a low proliferative activity and a favorable prognosis.",
author = "Lee, {Wen Ying} and Tzeng, {Ching Cherng} and Jin, {Ying Tai} and Nan-Haw Chow and Yip, {Chi Man} and Jenq-Chang Lee",
year = "1993",
month = "1",
day = "1",
doi = "10.1097/00006676-199301000-00023",
language = "English",
volume = "8",
pages = "127--132",
journal = "Pancreas",
issn = "0885-3177",
publisher = "Lippincott Williams and Wilkins",
number = "1",

}

Papillary cystic tumor of the pancreas : A case indistinguishable from oncocytic carcinoma. / Lee, Wen Ying; Tzeng, Ching Cherng; Jin, Ying Tai; Chow, Nan-Haw; Yip, Chi Man; Lee, Jenq-Chang.

In: Pancreas, Vol. 8, No. 1, 01.01.1993, p. 127-132.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Papillary cystic tumor of the pancreas

T2 - A case indistinguishable from oncocytic carcinoma

AU - Lee, Wen Ying

AU - Tzeng, Ching Cherng

AU - Jin, Ying Tai

AU - Chow, Nan-Haw

AU - Yip, Chi Man

AU - Lee, Jenq-Chang

PY - 1993/1/1

Y1 - 1993/1/1

N2 - A case of papillary cystic tumor (PCT) of the pancreas in a 55-year-old woman is described. She presented with a gradually enlarging and painless abdominal mass for >26 years. The tumor was encapsulated and measured 16 × 12 × 10 cm. The gross features and conventional light microscopic appearances of this tumor were consistent with the previously reported cases of PCT. Perineural and capsular invasions were found. In addition to the densely packed blue granules in the cytoplasm demonstrated by phosphotungstic acid-hematoxylin stain, ultrastructural study revealed the tumor cells to be packed with numerous mitochondria. These oncocytes comprised almost all the non-necrotic tumor areas. Therefore, this case was indistinguishable pathologically from oncocytic carcinoma of the pancreas. DNA flow cytometry showed a diploid pattern and low S phase fraction, indicating that the tumor has a low proliferative activity and a favorable prognosis.

AB - A case of papillary cystic tumor (PCT) of the pancreas in a 55-year-old woman is described. She presented with a gradually enlarging and painless abdominal mass for >26 years. The tumor was encapsulated and measured 16 × 12 × 10 cm. The gross features and conventional light microscopic appearances of this tumor were consistent with the previously reported cases of PCT. Perineural and capsular invasions were found. In addition to the densely packed blue granules in the cytoplasm demonstrated by phosphotungstic acid-hematoxylin stain, ultrastructural study revealed the tumor cells to be packed with numerous mitochondria. These oncocytes comprised almost all the non-necrotic tumor areas. Therefore, this case was indistinguishable pathologically from oncocytic carcinoma of the pancreas. DNA flow cytometry showed a diploid pattern and low S phase fraction, indicating that the tumor has a low proliferative activity and a favorable prognosis.

UR - http://www.scopus.com/inward/record.url?scp=0027396370&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027396370&partnerID=8YFLogxK

U2 - 10.1097/00006676-199301000-00023

DO - 10.1097/00006676-199301000-00023

M3 - Article

VL - 8

SP - 127

EP - 132

JO - Pancreas

JF - Pancreas

SN - 0885-3177

IS - 1

ER -