TY - JOUR
T1 - Particle handling in straight microfluidic channels via opposing electroosmotic and pressure-driven flows
AU - Huang, Kuan Da
AU - Yang, Sheng Chun
AU - Huang, Zhi Xiong
AU - Yang, Ruey Jen
N1 - Funding Information:
Acknowledgements The authors gratefully acknowledge the financial support provided to this study by the National Science Council of Taiwan under Grant Nos. NSC 95-2221-E-006-253 and NSC 95-2221-E-006-384-MY2.
PY - 2008/8
Y1 - 2008/8
N2 - The current study presents a method for producing recirculation zones in a straight microchannel using opposing pressure-driven and electrokinetically driven flows. The interaction of these two flow streams causes flow recirculation structures, which restricts the flow passage within the microchannel and causes a nozzle-like effect, thereby increasing the separation distance between particles in the fluid stream. Theoretical and experimental investigations are performed to investigate the effects of the applied electrical field intensity on the flow recirculation size, and the nozzle-like effect, respectively. In general, the results confirm that the proposed approach provides an effective means of achieving particle acceleration and separation distance within straight microchannels, and therefore provides a viable technique for improving particle manipulation and optical detection in conventional microfluidic devices.
AB - The current study presents a method for producing recirculation zones in a straight microchannel using opposing pressure-driven and electrokinetically driven flows. The interaction of these two flow streams causes flow recirculation structures, which restricts the flow passage within the microchannel and causes a nozzle-like effect, thereby increasing the separation distance between particles in the fluid stream. Theoretical and experimental investigations are performed to investigate the effects of the applied electrical field intensity on the flow recirculation size, and the nozzle-like effect, respectively. In general, the results confirm that the proposed approach provides an effective means of achieving particle acceleration and separation distance within straight microchannels, and therefore provides a viable technique for improving particle manipulation and optical detection in conventional microfluidic devices.
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U2 - 10.1007/s10404-007-0241-9
DO - 10.1007/s10404-007-0241-9
M3 - Article
AN - SCOPUS:46849117039
SN - 1613-4982
VL - 5
SP - 245
EP - 253
JO - Microfluidics and Nanofluidics
JF - Microfluidics and Nanofluidics
IS - 2
ER -