Patents and the development on polymer based nanomaterial (PAMAM dendrimer) for biomedical applications

Damaramadugu Rajasekhar, Pao-Chi Liao

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

Dendrimers have found extensive convention in varied fields of biomedical engineering. Particularly, polyamidoamine (PAMAM) dendrimers have been found to have unique properties, and also interesting researches in the field of biomedical engineering have been recognized, when compared to other class of dendrimers. PAMAM dendrimers are biofriendly synthetic substances, and broadly studied dendrimers for biomedical applications, especially as therapeutic compositions. The focus of this review (citing 188 references) is on PAMAM dendrimer developments for biomedical applications, with prominence on conjugations for their extensive applications in the field of biomedical engineering and comparisons between classical (Tomalia PAMAM dendrimers) and novel (Baker-Huang PAMAM dendrimers) PAMAM dendrimers are also discussed by covering recent patents on PAMAM dendrimers. Finally, the use of PAMAM dendrimers in the field of proteomics, especially for use in phosphopeptide enrichment is presented. The future work points at the promises of developments.

Original languageEnglish
Pages (from-to)159-174
Number of pages16
JournalRecent Patents on Biomedical Engineering
Volume5
Issue number2
DOIs
Publication statusPublished - 2012 Jan 1

Fingerprint

Dendrimers
Patents
Nanostructures
Nanostructured materials
Polymers
Biomedical Engineering
Biomedical engineering
Poly(amidoamine)
Phosphopeptides
Proteomics

All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Medicine (miscellaneous)
  • Biomedical Engineering

Cite this

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abstract = "Dendrimers have found extensive convention in varied fields of biomedical engineering. Particularly, polyamidoamine (PAMAM) dendrimers have been found to have unique properties, and also interesting researches in the field of biomedical engineering have been recognized, when compared to other class of dendrimers. PAMAM dendrimers are biofriendly synthetic substances, and broadly studied dendrimers for biomedical applications, especially as therapeutic compositions. The focus of this review (citing 188 references) is on PAMAM dendrimer developments for biomedical applications, with prominence on conjugations for their extensive applications in the field of biomedical engineering and comparisons between classical (Tomalia PAMAM dendrimers) and novel (Baker-Huang PAMAM dendrimers) PAMAM dendrimers are also discussed by covering recent patents on PAMAM dendrimers. Finally, the use of PAMAM dendrimers in the field of proteomics, especially for use in phosphopeptide enrichment is presented. The future work points at the promises of developments.",
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Patents and the development on polymer based nanomaterial (PAMAM dendrimer) for biomedical applications. / Rajasekhar, Damaramadugu; Liao, Pao-Chi.

In: Recent Patents on Biomedical Engineering, Vol. 5, No. 2, 01.01.2012, p. 159-174.

Research output: Contribution to journalReview article

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