Penile cancer in Taiwan - 20 years' experience at National Taiwan University Hospital

Tsu Yih Chiu, Ho-Shiang Huang, Ming Kuen Lai, Jun Chen, Teh Sheng Hsieh, Shih Chieh Chueh

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Abstract

To analyze the characteristics and prognostic factors of penile cancer in Taiwanese, we retrospectively reviewed the clinical data of patients with a diagnosis of penile cancer treated during a 20-year period (1977-1996) at National Taiwan University Hospital (NTUH). Of 71 patients treated for penile cancer during the study period, 17 were referred from other hospitals or clinics. Our analyses focused on the 54 previously untreated patient. Growth on the penis was the main symptom in all cases. Palpable inguinal lymph nodes were found only in 14 patient. All 54 patients with primary tumors were treated surgically. Pathologic examination showed squamous cell carcinoma (SCC) in 43 cases, extra-mammary Paget's disease in three, verrucous carcinoma in three, Bowen's disease in two, cutaneous lymphoma in two and basal cell carcinoma in one. Twenty-six (48%) patients had stage I penile cancer, 13 (24%) had stage II, seven (13%) had stage III, and eight (15%) had stage W cancer. The five-year survival rate was 78% among patients with SCC and 84% among those with nonsquamous malignancies (p=0.80). The five-year cumulative survival rates according to Jackson's cancer stage were 100% for patients with stage I, 88.9% for those with stage II, 66.7% for those with stage III, and 0% for those with stage IV (p<0.001). Tumor staging (p=0.027) and adjuvant chemotherapy (p=0.042) were found to be the most significant prognostic factors. Penile cancer accounted for 0.254% of all malignancies among male patients at the NTUH during the study period. Our findings indicate that penile cancer is uncommon in Taiwanese and its prognosis is closely related to tumor staging and management. Early diagnosis and appropriate treatment may lead to prolonged survival.

Original languageEnglish
Pages (from-to)673-678
Number of pages6
JournalJournal of the Formosan Medical Association
Volume97
Issue number10
Publication statusPublished - 1998 Oct 1

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Penile Neoplasms
Taiwan
Neoplasm Staging
Neoplasms
Squamous Cell Carcinoma
Survival Rate
Extramammary Paget's Disease
Verrucous Carcinoma
Bowen's Disease
Groin
Basal Cell Carcinoma
Penis
Adjuvant Chemotherapy
Early Diagnosis
Lymphoma
Lymph Nodes

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Chiu, Tsu Yih ; Huang, Ho-Shiang ; Lai, Ming Kuen ; Chen, Jun ; Hsieh, Teh Sheng ; Chueh, Shih Chieh. / Penile cancer in Taiwan - 20 years' experience at National Taiwan University Hospital. In: Journal of the Formosan Medical Association. 1998 ; Vol. 97, No. 10. pp. 673-678.
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abstract = "To analyze the characteristics and prognostic factors of penile cancer in Taiwanese, we retrospectively reviewed the clinical data of patients with a diagnosis of penile cancer treated during a 20-year period (1977-1996) at National Taiwan University Hospital (NTUH). Of 71 patients treated for penile cancer during the study period, 17 were referred from other hospitals or clinics. Our analyses focused on the 54 previously untreated patient. Growth on the penis was the main symptom in all cases. Palpable inguinal lymph nodes were found only in 14 patient. All 54 patients with primary tumors were treated surgically. Pathologic examination showed squamous cell carcinoma (SCC) in 43 cases, extra-mammary Paget's disease in three, verrucous carcinoma in three, Bowen's disease in two, cutaneous lymphoma in two and basal cell carcinoma in one. Twenty-six (48{\%}) patients had stage I penile cancer, 13 (24{\%}) had stage II, seven (13{\%}) had stage III, and eight (15{\%}) had stage W cancer. The five-year survival rate was 78{\%} among patients with SCC and 84{\%} among those with nonsquamous malignancies (p=0.80). The five-year cumulative survival rates according to Jackson's cancer stage were 100{\%} for patients with stage I, 88.9{\%} for those with stage II, 66.7{\%} for those with stage III, and 0{\%} for those with stage IV (p<0.001). Tumor staging (p=0.027) and adjuvant chemotherapy (p=0.042) were found to be the most significant prognostic factors. Penile cancer accounted for 0.254{\%} of all malignancies among male patients at the NTUH during the study period. Our findings indicate that penile cancer is uncommon in Taiwanese and its prognosis is closely related to tumor staging and management. Early diagnosis and appropriate treatment may lead to prolonged survival.",
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Penile cancer in Taiwan - 20 years' experience at National Taiwan University Hospital. / Chiu, Tsu Yih; Huang, Ho-Shiang; Lai, Ming Kuen; Chen, Jun; Hsieh, Teh Sheng; Chueh, Shih Chieh.

In: Journal of the Formosan Medical Association, Vol. 97, No. 10, 01.10.1998, p. 673-678.

Research output: Contribution to journalArticle

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N2 - To analyze the characteristics and prognostic factors of penile cancer in Taiwanese, we retrospectively reviewed the clinical data of patients with a diagnosis of penile cancer treated during a 20-year period (1977-1996) at National Taiwan University Hospital (NTUH). Of 71 patients treated for penile cancer during the study period, 17 were referred from other hospitals or clinics. Our analyses focused on the 54 previously untreated patient. Growth on the penis was the main symptom in all cases. Palpable inguinal lymph nodes were found only in 14 patient. All 54 patients with primary tumors were treated surgically. Pathologic examination showed squamous cell carcinoma (SCC) in 43 cases, extra-mammary Paget's disease in three, verrucous carcinoma in three, Bowen's disease in two, cutaneous lymphoma in two and basal cell carcinoma in one. Twenty-six (48%) patients had stage I penile cancer, 13 (24%) had stage II, seven (13%) had stage III, and eight (15%) had stage W cancer. The five-year survival rate was 78% among patients with SCC and 84% among those with nonsquamous malignancies (p=0.80). The five-year cumulative survival rates according to Jackson's cancer stage were 100% for patients with stage I, 88.9% for those with stage II, 66.7% for those with stage III, and 0% for those with stage IV (p<0.001). Tumor staging (p=0.027) and adjuvant chemotherapy (p=0.042) were found to be the most significant prognostic factors. Penile cancer accounted for 0.254% of all malignancies among male patients at the NTUH during the study period. Our findings indicate that penile cancer is uncommon in Taiwanese and its prognosis is closely related to tumor staging and management. Early diagnosis and appropriate treatment may lead to prolonged survival.

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