Percutaneous computed tomography-guided coaxial core biopsy for the diagnosis of pancreatic tumors

Yung Yeh Su, Yi Sheng Liu, Ying Jui Chao, Nai Jung Chiang, Chia Jui Yen, Hong Ming Tsai

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1 Citation (Scopus)

Abstract

Endoscopic, ultrasound-guided tissue acquisition (EUS-TA) with rapid on-site evaluation is recommended as a first choice in the diagnosis of pancreatic lesions. Since EUS facilities and rapid on-site evaluation are not widely available, even in medical centers, an alternative for precise diagnoses of pancreatic tumor is warranted. The percutaneous computed tomography-guided, core needle biopsy (CT-CNB) is a commonly applicable method for biopsies. Our institute has developed a fat-transversing approach for pancreatic biopsies which is able to approach most tumors in the pancreas without penetrating organs or vessels. Herein, we report a 15-year experiment of pancreatic tumor coaxial CT-CNB in 420 patients. The success rate of tissue yielding by the technique was 99.3%. The overall sensitivity, specificity, and accuracy were 93.2%, 100%, and 93.4%, respectively. The diagnostic accuracy could be increased to 96.4% in 2016–2018 (after the learning curve period). The overall complication rate was 8.6%. Neither life-threatening major complications, nor seeding through the biopsy tract, were observed. Our study supported the hypothesis that CT-CNB could be a complementary option for diagnostic tissue acquisition in patients with unresectable or metastatic pancreatic tumors when EUS-TA is either unsuitable or unavailable.

Original languageEnglish
Article number1633
JournalJournal of Clinical Medicine
Volume8
Issue number10
DOIs
Publication statusPublished - 2019 Oct

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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