Peritoneal tuberculosis with elevated serum CA125 mimicking peritoneal carcinomatosis on F-18 FDG-PET/CT

Chao Jung Chen, Wei-Jen Yao, Cheng-Yang Chou, Nan-Tsing Chiu, Bi-Fang Lee, Pei-Shan Wu

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

18F-fluorodeoxyglucose positron emission tomography (F-18 FDG-PET) plays an important role in differentiating benign from malignant tumors. However, some false-positive findings, such as tuberculosis, may occur. We report a case referred for F-18 FDG whole-body PET computed tomography (PET/CT) scan owing to an elevated serum cancer antigen 125 (CA125). An FDG-PET/CT scan showed multiple hypermetabolic foci in the mesentery and peritoneum with further increase of FDG uptake on the delayed scan, mimicking peritoneal carcinomatosis. Subsequent laparoscopic biopsy showed granulomatous inflammation, and tuberculosis polymerase chain reaction showed a positive result. Serum CA125 returned to normal following treatment with anti-tuberculosis drugs. Peritoneal tuberculosis should be considered as a differential diagnosis in a tuberculosis endemic region.

Original languageEnglish
Pages (from-to)525-527
Number of pages3
JournalAnnals of Nuclear Medicine
Volume22
Issue number6
DOIs
Publication statusPublished - 2008 Jul 1

Fingerprint

Tuberculous Peritonitis
Tuberculosis
Tomography
Carcinoma
Antigens
Serum
Neoplasms
Mesentery
Peritoneum
Fluorodeoxyglucose F18
Positron-Emission Tomography
Differential Diagnosis
Inflammation
Biopsy
Polymerase Chain Reaction
Pharmaceutical Preparations

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

@article{0703e0816d4d4c0a90d5c7a9ec08c9af,
title = "Peritoneal tuberculosis with elevated serum CA125 mimicking peritoneal carcinomatosis on F-18 FDG-PET/CT",
abstract = "18F-fluorodeoxyglucose positron emission tomography (F-18 FDG-PET) plays an important role in differentiating benign from malignant tumors. However, some false-positive findings, such as tuberculosis, may occur. We report a case referred for F-18 FDG whole-body PET computed tomography (PET/CT) scan owing to an elevated serum cancer antigen 125 (CA125). An FDG-PET/CT scan showed multiple hypermetabolic foci in the mesentery and peritoneum with further increase of FDG uptake on the delayed scan, mimicking peritoneal carcinomatosis. Subsequent laparoscopic biopsy showed granulomatous inflammation, and tuberculosis polymerase chain reaction showed a positive result. Serum CA125 returned to normal following treatment with anti-tuberculosis drugs. Peritoneal tuberculosis should be considered as a differential diagnosis in a tuberculosis endemic region.",
author = "Chen, {Chao Jung} and Wei-Jen Yao and Cheng-Yang Chou and Nan-Tsing Chiu and Bi-Fang Lee and Pei-Shan Wu",
year = "2008",
month = "7",
day = "1",
doi = "10.1007/s12149-008-0139-y",
language = "English",
volume = "22",
pages = "525--527",
journal = "Annals of Nuclear Medicine",
issn = "0914-7187",
publisher = "Springer Japan",
number = "6",

}

Peritoneal tuberculosis with elevated serum CA125 mimicking peritoneal carcinomatosis on F-18 FDG-PET/CT. / Chen, Chao Jung; Yao, Wei-Jen; Chou, Cheng-Yang; Chiu, Nan-Tsing; Lee, Bi-Fang; Wu, Pei-Shan.

In: Annals of Nuclear Medicine, Vol. 22, No. 6, 01.07.2008, p. 525-527.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Peritoneal tuberculosis with elevated serum CA125 mimicking peritoneal carcinomatosis on F-18 FDG-PET/CT

AU - Chen, Chao Jung

AU - Yao, Wei-Jen

AU - Chou, Cheng-Yang

AU - Chiu, Nan-Tsing

AU - Lee, Bi-Fang

AU - Wu, Pei-Shan

PY - 2008/7/1

Y1 - 2008/7/1

N2 - 18F-fluorodeoxyglucose positron emission tomography (F-18 FDG-PET) plays an important role in differentiating benign from malignant tumors. However, some false-positive findings, such as tuberculosis, may occur. We report a case referred for F-18 FDG whole-body PET computed tomography (PET/CT) scan owing to an elevated serum cancer antigen 125 (CA125). An FDG-PET/CT scan showed multiple hypermetabolic foci in the mesentery and peritoneum with further increase of FDG uptake on the delayed scan, mimicking peritoneal carcinomatosis. Subsequent laparoscopic biopsy showed granulomatous inflammation, and tuberculosis polymerase chain reaction showed a positive result. Serum CA125 returned to normal following treatment with anti-tuberculosis drugs. Peritoneal tuberculosis should be considered as a differential diagnosis in a tuberculosis endemic region.

AB - 18F-fluorodeoxyglucose positron emission tomography (F-18 FDG-PET) plays an important role in differentiating benign from malignant tumors. However, some false-positive findings, such as tuberculosis, may occur. We report a case referred for F-18 FDG whole-body PET computed tomography (PET/CT) scan owing to an elevated serum cancer antigen 125 (CA125). An FDG-PET/CT scan showed multiple hypermetabolic foci in the mesentery and peritoneum with further increase of FDG uptake on the delayed scan, mimicking peritoneal carcinomatosis. Subsequent laparoscopic biopsy showed granulomatous inflammation, and tuberculosis polymerase chain reaction showed a positive result. Serum CA125 returned to normal following treatment with anti-tuberculosis drugs. Peritoneal tuberculosis should be considered as a differential diagnosis in a tuberculosis endemic region.

UR - http://www.scopus.com/inward/record.url?scp=48749095617&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=48749095617&partnerID=8YFLogxK

U2 - 10.1007/s12149-008-0139-y

DO - 10.1007/s12149-008-0139-y

M3 - Article

C2 - 18670860

AN - SCOPUS:48749095617

VL - 22

SP - 525

EP - 527

JO - Annals of Nuclear Medicine

JF - Annals of Nuclear Medicine

SN - 0914-7187

IS - 6

ER -