TY - JOUR
T1 - Pollen of Broussonetia papyrifera
T2 - An emerging aeroallergen associated with allergic illness in Taiwan
AU - Wu, Pei Chih
AU - Su, Huey Jen
AU - Lung, Shih Chun Candice
AU - Chen, Mu Jean
AU - Lin, Wei Ping
N1 - Funding Information:
The authors are in great debt to many temporary assistants who have helped over the time for samples collection year-round. The study was in part supported by the grant from the Taiwan National Science Council (NSC99-2621-M-309-001). The authors do not have a commercial and other association that might pose a conflict of interest. This manuscript has not been submitted or accepted elsewhere and all authors have seen and approved the content and contributed significantly to the work. This manuscript was edited by Wallace Academic Editing.
Funding Information:
The authors are in great debt to many temporary assistants who have helped over the time for samples collection year-round. The study was in part supported by the grant from the Taiwan National Science Council ( NSC99-2621-M-309-001 ). The authors do not have a commercial and other association that might pose a conflict of interest. This manuscript has not been submitted or accepted elsewhere and all authors have seen and approved the content and contributed significantly to the work. This manuscript was edited by Wallace Academic Editing.
Publisher Copyright:
© 2018
PY - 2019/3/20
Y1 - 2019/3/20
N2 - Pollen has long been recognized as a major allergen, having diverse patterns of allergenicity caused by differences in climate, geography, and vegetation. Our research aimed to explore the role of a regionally dominant pollen in Taiwan, Broussonetia papyrifera, on clinical sensitization and daily 5collected and extracted for a skin prick test on 30 volunteers recruited from a medical college. Daily atmospheric pollen levels were measured using a Burkard 7-day volumetric trap. The association between daily atmospheric pollen levels and clinic visits for allergic illness was examined using a generalized additive model with a normal assumption. After excluding four participants with a positive response to a negative control, 10 participants (38.4%) were determined to be sensitive to B. papyrifera pollen extract. The three-day lagged concentration of B. papyrifera pollen exhibited the highest risk of daily asthma visits (relative risk [RR] = 1.166, 95% confidence interval [CI]: 1.014–1.341) and allergic rhinitis visits (RR = 1.119, 95% CI: 0.916–1.367) when the pollen increased equally in magnitude to its mean. Our study is the first to provide evidence indicating that the most dominant airborne pollen in Taiwan, B. papyrifera, plays a major role in sensitization and clinic visits for asthma and allergic rhinitis, thus highlighting the need to integrate aeroallergen monitoring with clinical diagnosis.
AB - Pollen has long been recognized as a major allergen, having diverse patterns of allergenicity caused by differences in climate, geography, and vegetation. Our research aimed to explore the role of a regionally dominant pollen in Taiwan, Broussonetia papyrifera, on clinical sensitization and daily 5collected and extracted for a skin prick test on 30 volunteers recruited from a medical college. Daily atmospheric pollen levels were measured using a Burkard 7-day volumetric trap. The association between daily atmospheric pollen levels and clinic visits for allergic illness was examined using a generalized additive model with a normal assumption. After excluding four participants with a positive response to a negative control, 10 participants (38.4%) were determined to be sensitive to B. papyrifera pollen extract. The three-day lagged concentration of B. papyrifera pollen exhibited the highest risk of daily asthma visits (relative risk [RR] = 1.166, 95% confidence interval [CI]: 1.014–1.341) and allergic rhinitis visits (RR = 1.119, 95% CI: 0.916–1.367) when the pollen increased equally in magnitude to its mean. Our study is the first to provide evidence indicating that the most dominant airborne pollen in Taiwan, B. papyrifera, plays a major role in sensitization and clinic visits for asthma and allergic rhinitis, thus highlighting the need to integrate aeroallergen monitoring with clinical diagnosis.
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UR - http://www.scopus.com/inward/citedby.url?scp=85058215542&partnerID=8YFLogxK
U2 - 10.1016/j.scitotenv.2018.11.324
DO - 10.1016/j.scitotenv.2018.11.324
M3 - Article
C2 - 30677945
AN - SCOPUS:85058215542
SN - 0048-9697
VL - 657
SP - 804
EP - 810
JO - Science of the Total Environment
JF - Science of the Total Environment
ER -
