Polyphenol-assisted assembly of Au-deposited polylactic acid microneedles for SERS sensing and antibacterial photodynamic therapy

Zi Chun Chia; Yi Lun Chen; Cheng Hsun Chuang; Chou Hsun Hsieh; Ya Jyun Chen; Kuan Hsu Chen; Tzu Chi Huang; Mei Chin Chen; Chih Chia Huang

doi:10.1039/d3cc00733b

Polyphenol-assisted assembly of Au-deposited polylactic acid microneedles for SERS sensing and antibacterial photodynamic therapy

Zi Chun Chia, Yi Lun Chen, Cheng Hsun Chuang, Chou Hsun Hsieh, Ya Jyun Chen, Kuan Hsu Chen, Tzu Chi Huang, Mei Chin Chen, Chih Chia Huang

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

3D SERS microneedles with self-assembled AuNPs were fabricated with tannic acid (chemical glue and reductant) on polylactic acid microneedles for in-depth chemical and biomolecular analysis, with LOD values below 200 ppb for small molecules and 10² CFU cm⁻² for bacteria. The MB/Au-microneedles were used for photodynamic therapy with SERS-monitored photosensitizer degradation.

Original language	English
Pages (from-to)	6339-6342
Number of pages	4
Journal	Chemical Communications
Volume	59
Issue number	42
DOIs	https://doi.org/10.1039/d3cc00733b
Publication status	Published - 2023 Apr 20

All Science Journal Classification (ASJC) codes

Electronic, Optical and Magnetic Materials
General Chemistry
Ceramics and Composites
Metals and Alloys
Materials Chemistry
Surfaces, Coatings and Films
Catalysis

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10.1039/d3cc00733b

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title = "Polyphenol-assisted assembly of Au-deposited polylactic acid microneedles for SERS sensing and antibacterial photodynamic therapy",

abstract = "3D SERS microneedles with self-assembled AuNPs were fabricated with tannic acid (chemical glue and reductant) on polylactic acid microneedles for in-depth chemical and biomolecular analysis, with LOD values below 200 ppb for small molecules and 102 CFU cm−2 for bacteria. The MB/Au-microneedles were used for photodynamic therapy with SERS-monitored photosensitizer degradation.",

author = "Chia, {Zi Chun} and Chen, {Yi Lun} and Chuang, {Cheng Hsun} and Hsieh, {Chou Hsun} and Chen, {Ya Jyun} and Chen, {Kuan Hsu} and Huang, {Tzu Chi} and Chen, {Mei Chin} and Huang, {Chih Chia}",

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doi = "10.1039/d3cc00733b",

language = "English",

volume = "59",

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T1 - Polyphenol-assisted assembly of Au-deposited polylactic acid microneedles for SERS sensing and antibacterial photodynamic therapy

AU - Chia, Zi Chun

AU - Chen, Yi Lun

AU - Chuang, Cheng Hsun

AU - Hsieh, Chou Hsun

AU - Chen, Ya Jyun

AU - Chen, Kuan Hsu

AU - Huang, Tzu Chi

AU - Chen, Mei Chin

AU - Huang, Chih Chia

PY - 2023/4/20

Y1 - 2023/4/20

N2 - 3D SERS microneedles with self-assembled AuNPs were fabricated with tannic acid (chemical glue and reductant) on polylactic acid microneedles for in-depth chemical and biomolecular analysis, with LOD values below 200 ppb for small molecules and 102 CFU cm−2 for bacteria. The MB/Au-microneedles were used for photodynamic therapy with SERS-monitored photosensitizer degradation.

AB - 3D SERS microneedles with self-assembled AuNPs were fabricated with tannic acid (chemical glue and reductant) on polylactic acid microneedles for in-depth chemical and biomolecular analysis, with LOD values below 200 ppb for small molecules and 102 CFU cm−2 for bacteria. The MB/Au-microneedles were used for photodynamic therapy with SERS-monitored photosensitizer degradation.

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SN - 1359-7345

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SP - 6339

EP - 6342

JO - Chemical Communications

JF - Chemical Communications

IS - 42

ER -

Polyphenol-assisted assembly of Au-deposited polylactic acid microneedles for SERS sensing and antibacterial photodynamic therapy

Abstract

All Science Journal Classification (ASJC) codes

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