Post-discharge use of antipsychotics in patients with hospital-acquired delirium and associated risk of mortality – A population-based nested case-control study

Daniel Hsiang Te Tsai; Wei Hung Chang; Hsiang Wen Lin; Swu Jane Lin; Shih Chieh Shao; Edward Chia Cheng Lai

doi:10.1016/j.ajp.2023.103533

Post-discharge use of antipsychotics in patients with hospital-acquired delirium and associated risk of mortality – A population-based nested case-control study

Daniel Hsiang Te Tsai, Wei Hung Chang, Hsiang Wen Lin, Swu Jane Lin, Shih Chieh Shao, Edward Chia Cheng Lai

Research output: Contribution to journal › Article › peer-review

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Abstract

Objective: To evaluate post-discharge use of antipsychotics in patients with incident hospital-acquired delirium and the associated risk of mortality. Methods: We conducted a nested case-control study for patients newly diagnosed with hospital-acquired delirium and subsequently discharged from hospital using Taiwan's National Health Insurance Database (NHID) from 2011 to 2018. Results: The use of antipsychotics after discharge did not increase the risk of mortality (adjusted OR: 1·03; 95% CI: 0·98–1·09). Conclusions: The findings suggested that using antipsychotics after discharge in patients with hospital-acquired delirium may not increase the risk of mortality.

Original language	English
Article number	103533
Journal	Asian Journal of Psychiatry
Volume	83
DOIs	https://doi.org/10.1016/j.ajp.2023.103533
Publication status	Published - 2023 May

All Science Journal Classification (ASJC) codes

General Psychology
Psychiatry and Mental health

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10.1016/j.ajp.2023.103533

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title = "Post-discharge use of antipsychotics in patients with hospital-acquired delirium and associated risk of mortality – A population-based nested case-control study",

abstract = "Objective: To evaluate post-discharge use of antipsychotics in patients with incident hospital-acquired delirium and the associated risk of mortality. Methods: We conducted a nested case-control study for patients newly diagnosed with hospital-acquired delirium and subsequently discharged from hospital using Taiwan's National Health Insurance Database (NHID) from 2011 to 2018. Results: The use of antipsychotics after discharge did not increase the risk of mortality (adjusted OR: 1·03; 95% CI: 0·98–1·09). Conclusions: The findings suggested that using antipsychotics after discharge in patients with hospital-acquired delirium may not increase the risk of mortality.",

author = "Tsai, {Daniel Hsiang Te} and Chang, {Wei Hung} and Lin, {Hsiang Wen} and Lin, {Swu Jane} and Shao, {Shih Chieh} and Lai, {Edward Chia Cheng}",

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year = "2023",

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doi = "10.1016/j.ajp.2023.103533",

language = "English",

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T1 - Post-discharge use of antipsychotics in patients with hospital-acquired delirium and associated risk of mortality – A population-based nested case-control study

AU - Tsai, Daniel Hsiang Te

AU - Chang, Wei Hung

AU - Lin, Hsiang Wen

AU - Lin, Swu Jane

AU - Shao, Shih Chieh

AU - Lai, Edward Chia Cheng

PY - 2023/5

Y1 - 2023/5

N2 - Objective: To evaluate post-discharge use of antipsychotics in patients with incident hospital-acquired delirium and the associated risk of mortality. Methods: We conducted a nested case-control study for patients newly diagnosed with hospital-acquired delirium and subsequently discharged from hospital using Taiwan's National Health Insurance Database (NHID) from 2011 to 2018. Results: The use of antipsychotics after discharge did not increase the risk of mortality (adjusted OR: 1·03; 95% CI: 0·98–1·09). Conclusions: The findings suggested that using antipsychotics after discharge in patients with hospital-acquired delirium may not increase the risk of mortality.

AB - Objective: To evaluate post-discharge use of antipsychotics in patients with incident hospital-acquired delirium and the associated risk of mortality. Methods: We conducted a nested case-control study for patients newly diagnosed with hospital-acquired delirium and subsequently discharged from hospital using Taiwan's National Health Insurance Database (NHID) from 2011 to 2018. Results: The use of antipsychotics after discharge did not increase the risk of mortality (adjusted OR: 1·03; 95% CI: 0·98–1·09). Conclusions: The findings suggested that using antipsychotics after discharge in patients with hospital-acquired delirium may not increase the risk of mortality.

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Post-discharge use of antipsychotics in patients with hospital-acquired delirium and associated risk of mortality – A population-based nested case-control study

Abstract

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