Postirradiation osteogenic sarcoma of the maxilla - Case report

Osteogenic sarcoma is an uncommon malignant neoplasm which is usually seen in teenagers. The site of predilection is at the metaphysis of long bones, particularly of the lower limbs. Osteogenic sarcomas of the head and neck, especially the maxilla, are rare. The incidence of irradiation-induced sarcoma is between 0.03% and 0.22%. The treatment of choice for postirradiation sarcoma is radical operation. It is resistant to radiotherapy or chemotherapy. We report a 44-year-old male nasopharyngeal carcinoma patient who had received radiotherapy in 1990. He has suffered from nasal bleeding and palatal ulceration since 1995. Osteogenic sarcoma of the maxilla was confirmed by histological examination. He received left total maxillectomy later. The post-operation course was smooth. There has been no evidence of recurrence till now.