TY - JOUR
T1 - Prenatal diagnosis of cleft palate by three-dimensional ultrasound
AU - Chen, Min Long
AU - Chang, Chiung Hsin
AU - Yu, Chen Hsiang
AU - Cheng, Yueh Chin
AU - Chang, Fong Ming
N1 - Funding Information:
This study was supported in part by grants from National Science Council, Taipei, Taiwan, to Dr. Chiung-Hsin Chang (NSC 89-2314-B006-069, NSC89-2314-B006-115) to Dr. Chen-Hsiang Yu (NSC88-2314-B006-131), and to Dr. Fong-Ming Chang (NSC 89-2314-B006-065, NSC 89-2314-B006-113). The authors are grateful to Hsi-Yao Chen for his advice and to Wen-Chu Chen and Yi-Jen Wang for their assistance.
PY - 2001
Y1 - 2001
N2 - Prenatal diagnosis of cleft palate is very important to prenatal consultation and management after birth. To examine if three-dimensional (3-D) ultrasound (US) is an accurate diagnostic method for clinical use, we analyzed our experience in detecting cleft palate by 3-D US. From June 1996 to January 2000, 21 fetuses with facial clefts were scanned by 2-D US, as well as by 3-D US. The coronal and oblique planes were reconstructed by 3-D US to detect the cleft palate. In addition, level II US was performed to find any possibly associated anomalies. All the scans were recorded on optic disks for final analysis. In our study, the gestational age when prenatal diagnosis was made by US initially was between 20 and 34 weeks. The accuracy for prenatal diagnosis of cleft lip with or without cleft palate by 3-D US was 100%, which was superior to that by 2-D US (p < 0.05). In addition, we proposed a novel method to evaluate the cleft palate systemically by 3-D US. In conclusion, from our study, fetuses with cleft lip combined with or without cleft palate can be easily differentiated by 3-D US. The reconstruction of coronal and oblique planes by 3-D US is a powerful tool for detecting cleft palate.
AB - Prenatal diagnosis of cleft palate is very important to prenatal consultation and management after birth. To examine if three-dimensional (3-D) ultrasound (US) is an accurate diagnostic method for clinical use, we analyzed our experience in detecting cleft palate by 3-D US. From June 1996 to January 2000, 21 fetuses with facial clefts were scanned by 2-D US, as well as by 3-D US. The coronal and oblique planes were reconstructed by 3-D US to detect the cleft palate. In addition, level II US was performed to find any possibly associated anomalies. All the scans were recorded on optic disks for final analysis. In our study, the gestational age when prenatal diagnosis was made by US initially was between 20 and 34 weeks. The accuracy for prenatal diagnosis of cleft lip with or without cleft palate by 3-D US was 100%, which was superior to that by 2-D US (p < 0.05). In addition, we proposed a novel method to evaluate the cleft palate systemically by 3-D US. In conclusion, from our study, fetuses with cleft lip combined with or without cleft palate can be easily differentiated by 3-D US. The reconstruction of coronal and oblique planes by 3-D US is a powerful tool for detecting cleft palate.
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U2 - 10.1016/S0301-5629(01)00403-3
DO - 10.1016/S0301-5629(01)00403-3
M3 - Article
C2 - 11527587
AN - SCOPUS:0034861357
SN - 0301-5629
VL - 27
SP - 1017
EP - 1023
JO - Ultrasound in Medicine and Biology
JF - Ultrasound in Medicine and Biology
IS - 8
ER -