Collagen which is predominant in the extracellular matrix, serves as a support for the connective tissues. It, and its derived matrices have been used as bioprostheses for burn wound dressings and tissues templates due to their biocompatibility. Since collagen can be present in different forms, to evaluate and standardize experimental models, collagen fibrillar matrices (CFM) were reconstituted as native type collagen fibrils from purified pepsin soluble type I collagen. The in vitro CFM contraction model developed allowed us to study the effects of the concentration of collagen on CFM contraction by fibroblasts.
|Number of pages||12|
|Journal||Biomedical Engineering - Applications, Basis and Communications|
|Publication status||Published - 1993 Jan 1|
All Science Journal Classification (ASJC) codes
- Biomedical Engineering