Primäre humane Demodikose: Eine Erkrankung sui generis

Translated title of the contribution: Primary human demodicosis: A disease sui generis

Chao-Kai Hsu, A. Zink, K. J. Wei, E. Dzika, G. Plewig, W. Chen

Research output: Contribution to journalReview article

Abstract

Human Demodex mites (Demodex folliculorum and Demodex brevis) are unique in that they are an obligate human ectoparasite that can inhabit the pilosebaceous unit lifelong without causing obvious host immune response in most cases. The mode of symbiosis between humans and human Demodex mites is unclear, while the pathogenicity of human Demodex mites in many inflammatory skin diseases is now better understood. Primary human demodicosis is a skin disease sui generis not associated with local or systemic immunosuppression. Diagnosis is often underestimated and differentiation from folliculitis, papulopustular rosacea and perioral dermatitis is not always straightforward. Dependent on the morphology and degree of inflammation, the clinical manifestations can be classified into spinulate, papulopustular, nodulocystic, crustic and fulminant demodicosis. Therapy success can be achieved only with acaricides/arachidicides. The effective doses, optimal regimen and antimicrobial resistance remain to be determined.

Original languageGerman
Pages (from-to)189-194
Number of pages6
JournalHautarzt
Volume66
Issue number3
DOIs
Publication statusPublished - 2015 Mar 19

Fingerprint

Mites
Skin Diseases
Perioral Dermatitis
Acaricides
Folliculitis
Rosacea
Symbiosis
Immunosuppression
Virulence
Inflammation
Therapeutics

All Science Journal Classification (ASJC) codes

  • Dermatology

Cite this

Hsu, C-K., Zink, A., Wei, K. J., Dzika, E., Plewig, G., & Chen, W. (2015). Primäre humane Demodikose: Eine Erkrankung sui generis. Hautarzt, 66(3), 189-194. https://doi.org/10.1007/s00105-015-3595-z
Hsu, Chao-Kai ; Zink, A. ; Wei, K. J. ; Dzika, E. ; Plewig, G. ; Chen, W. / Primäre humane Demodikose : Eine Erkrankung sui generis. In: Hautarzt. 2015 ; Vol. 66, No. 3. pp. 189-194.
@article{ce834def47cb46e0862b43312025e52a,
title = "Prim{\"a}re humane Demodikose: Eine Erkrankung sui generis",
abstract = "Human Demodex mites (Demodex folliculorum and Demodex brevis) are unique in that they are an obligate human ectoparasite that can inhabit the pilosebaceous unit lifelong without causing obvious host immune response in most cases. The mode of symbiosis between humans and human Demodex mites is unclear, while the pathogenicity of human Demodex mites in many inflammatory skin diseases is now better understood. Primary human demodicosis is a skin disease sui generis not associated with local or systemic immunosuppression. Diagnosis is often underestimated and differentiation from folliculitis, papulopustular rosacea and perioral dermatitis is not always straightforward. Dependent on the morphology and degree of inflammation, the clinical manifestations can be classified into spinulate, papulopustular, nodulocystic, crustic and fulminant demodicosis. Therapy success can be achieved only with acaricides/arachidicides. The effective doses, optimal regimen and antimicrobial resistance remain to be determined.",
author = "Chao-Kai Hsu and A. Zink and Wei, {K. J.} and E. Dzika and G. Plewig and W. Chen",
year = "2015",
month = "3",
day = "19",
doi = "10.1007/s00105-015-3595-z",
language = "German",
volume = "66",
pages = "189--194",
journal = "Hautarzt",
issn = "0017-8470",
publisher = "Springer Verlag",
number = "3",

}

Hsu, C-K, Zink, A, Wei, KJ, Dzika, E, Plewig, G & Chen, W 2015, 'Primäre humane Demodikose: Eine Erkrankung sui generis', Hautarzt, vol. 66, no. 3, pp. 189-194. https://doi.org/10.1007/s00105-015-3595-z

Primäre humane Demodikose : Eine Erkrankung sui generis. / Hsu, Chao-Kai; Zink, A.; Wei, K. J.; Dzika, E.; Plewig, G.; Chen, W.

In: Hautarzt, Vol. 66, No. 3, 19.03.2015, p. 189-194.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Primäre humane Demodikose

T2 - Eine Erkrankung sui generis

AU - Hsu, Chao-Kai

AU - Zink, A.

AU - Wei, K. J.

AU - Dzika, E.

AU - Plewig, G.

AU - Chen, W.

PY - 2015/3/19

Y1 - 2015/3/19

N2 - Human Demodex mites (Demodex folliculorum and Demodex brevis) are unique in that they are an obligate human ectoparasite that can inhabit the pilosebaceous unit lifelong without causing obvious host immune response in most cases. The mode of symbiosis between humans and human Demodex mites is unclear, while the pathogenicity of human Demodex mites in many inflammatory skin diseases is now better understood. Primary human demodicosis is a skin disease sui generis not associated with local or systemic immunosuppression. Diagnosis is often underestimated and differentiation from folliculitis, papulopustular rosacea and perioral dermatitis is not always straightforward. Dependent on the morphology and degree of inflammation, the clinical manifestations can be classified into spinulate, papulopustular, nodulocystic, crustic and fulminant demodicosis. Therapy success can be achieved only with acaricides/arachidicides. The effective doses, optimal regimen and antimicrobial resistance remain to be determined.

AB - Human Demodex mites (Demodex folliculorum and Demodex brevis) are unique in that they are an obligate human ectoparasite that can inhabit the pilosebaceous unit lifelong without causing obvious host immune response in most cases. The mode of symbiosis between humans and human Demodex mites is unclear, while the pathogenicity of human Demodex mites in many inflammatory skin diseases is now better understood. Primary human demodicosis is a skin disease sui generis not associated with local or systemic immunosuppression. Diagnosis is often underestimated and differentiation from folliculitis, papulopustular rosacea and perioral dermatitis is not always straightforward. Dependent on the morphology and degree of inflammation, the clinical manifestations can be classified into spinulate, papulopustular, nodulocystic, crustic and fulminant demodicosis. Therapy success can be achieved only with acaricides/arachidicides. The effective doses, optimal regimen and antimicrobial resistance remain to be determined.

UR - http://www.scopus.com/inward/record.url?scp=84925488235&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84925488235&partnerID=8YFLogxK

U2 - 10.1007/s00105-015-3595-z

DO - 10.1007/s00105-015-3595-z

M3 - Review article

C2 - 25744530

AN - SCOPUS:84925488235

VL - 66

SP - 189

EP - 194

JO - Hautarzt

JF - Hautarzt

SN - 0017-8470

IS - 3

ER -

Hsu C-K, Zink A, Wei KJ, Dzika E, Plewig G, Chen W. Primäre humane Demodikose: Eine Erkrankung sui generis. Hautarzt. 2015 Mar 19;66(3):189-194. https://doi.org/10.1007/s00105-015-3595-z