Primäre humane Demodikose: Eine Erkrankung sui generis

Translated title of the contribution: Primary human demodicosis: A disease sui generis

C. K. Hsu, A. Zink, K. J. Wei, E. Dzika, G. Plewig, W. Chen

Research output: Contribution to journalReview articlepeer-review

2 Citations (Scopus)


Human Demodex mites (Demodex folliculorum and Demodex brevis) are unique in that they are an obligate human ectoparasite that can inhabit the pilosebaceous unit lifelong without causing obvious host immune response in most cases. The mode of symbiosis between humans and human Demodex mites is unclear, while the pathogenicity of human Demodex mites in many inflammatory skin diseases is now better understood. Primary human demodicosis is a skin disease sui generis not associated with local or systemic immunosuppression. Diagnosis is often underestimated and differentiation from folliculitis, papulopustular rosacea and perioral dermatitis is not always straightforward. Dependent on the morphology and degree of inflammation, the clinical manifestations can be classified into spinulate, papulopustular, nodulocystic, crustic and fulminant demodicosis. Therapy success can be achieved only with acaricides/arachidicides. The effective doses, optimal regimen and antimicrobial resistance remain to be determined.

Translated title of the contributionPrimary human demodicosis: A disease sui generis
Original languageGerman
Pages (from-to)189-194
Number of pages6
Issue number3
Publication statusPublished - 2015 Mar 19

All Science Journal Classification (ASJC) codes

  • Dermatology


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