Probing conformational transitions of polymer chains by microrheology

Chih Hsing Huang, Yen Ching Li, Yi Qi Yeh, U. Ser Jeng, Hsien-Hung Wei, Jeng-Shiung Jan

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

We report the first quantitative demonstration of the use of particle tracking microrheology (PTμR) in probing the pH-induced coil-globule transition (CGT) of poly-2-vinylpyridine (P2VP). The calculated radii R of the P2VP coils and globules are found to vary with molecular weight M respectively according to: R∞M0.592 ± 0.006 and R∞M 0.339 ± 0.010, in excellent agreement with the classical Flory-de Gennes theory. The sphere-like small-angle X-ray scattering spectrum and the sharp rise in pyrene emission suggest that the observed CGT is likely triggered by drastic changes in the chain's hydrophobicity, sensitive to the degree of protonation near the coil-globule transition point. A more in-depth theoretical analysis further reveals that the phenomenon strongly depends on interplays between excluded-volume, electrostatic, and hydrophobic interactions at the subunit level of a P2VP chain. This new application of PTμR could have potential uses in exploring the physics of a variety of polymer systems at the nano/molecular scales.

Original languageEnglish
Pages (from-to)3168-3177
Number of pages10
Journalpolymer
Volume55
Issue number14
DOIs
Publication statusPublished - 2014 Jun 19

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Protonation
Pyrene
Hydrophobicity
X ray scattering
Electrostatics
Polymers
Demonstrations
Physics
Molecular weight
poly(2-vinylpyridine)

All Science Journal Classification (ASJC) codes

  • Organic Chemistry
  • Polymers and Plastics

Cite this

Huang, C. H., Li, Y. C., Yeh, Y. Q., Jeng, U. S., Wei, H-H., & Jan, J-S. (2014). Probing conformational transitions of polymer chains by microrheology. polymer, 55(14), 3168-3177. https://doi.org/10.1016/j.polymer.2014.05.001
Huang, Chih Hsing ; Li, Yen Ching ; Yeh, Yi Qi ; Jeng, U. Ser ; Wei, Hsien-Hung ; Jan, Jeng-Shiung. / Probing conformational transitions of polymer chains by microrheology. In: polymer. 2014 ; Vol. 55, No. 14. pp. 3168-3177.
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Huang, CH, Li, YC, Yeh, YQ, Jeng, US, Wei, H-H & Jan, J-S 2014, 'Probing conformational transitions of polymer chains by microrheology', polymer, vol. 55, no. 14, pp. 3168-3177. https://doi.org/10.1016/j.polymer.2014.05.001

Probing conformational transitions of polymer chains by microrheology. / Huang, Chih Hsing; Li, Yen Ching; Yeh, Yi Qi; Jeng, U. Ser; Wei, Hsien-Hung; Jan, Jeng-Shiung.

In: polymer, Vol. 55, No. 14, 19.06.2014, p. 3168-3177.

Research output: Contribution to journalArticle

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AU - Yeh, Yi Qi

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AU - Jan, Jeng-Shiung

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N2 - We report the first quantitative demonstration of the use of particle tracking microrheology (PTμR) in probing the pH-induced coil-globule transition (CGT) of poly-2-vinylpyridine (P2VP). The calculated radii R of the P2VP coils and globules are found to vary with molecular weight M respectively according to: R∞M0.592 ± 0.006 and R∞M 0.339 ± 0.010, in excellent agreement with the classical Flory-de Gennes theory. The sphere-like small-angle X-ray scattering spectrum and the sharp rise in pyrene emission suggest that the observed CGT is likely triggered by drastic changes in the chain's hydrophobicity, sensitive to the degree of protonation near the coil-globule transition point. A more in-depth theoretical analysis further reveals that the phenomenon strongly depends on interplays between excluded-volume, electrostatic, and hydrophobic interactions at the subunit level of a P2VP chain. This new application of PTμR could have potential uses in exploring the physics of a variety of polymer systems at the nano/molecular scales.

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