Psoriasis in a 3-month-old infant with Kawasaki disease

Yi Chen Liao, Yu-Yun Lee

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Kawasaki disease (KD) or mucocutaneous lymph node syndrome is a systemic vasculitis of unknown etiology affecting young children. Typical cutaneous manifestations of KD are polymorphous, including maculopapular or morbilliform rash and erythroderma. Occurrence of psoriasis following KD is rare. Herein we report a case of new onset of psoriasis in a 3-month-old that flared after a typical clinical case of KD, manifesting spiking fever, diffuse redness and fissuring of the lips, bilateral conjunctiva injection, injected throat, left cervical lymphadenopathy, erythema and desquamation of the lips, cheeks, hands, feet and perianal area, and a generalized maculopapular eruption. In addition, erythema and induration of the BCG vaccination site and coronary artery dilatation were noted. After fading of the initial rash, the patient developed widespread psoriasiform papules and plaques involving the face and extremities. The cheeks, lips and nail involvement with subunqual hyperkeratosis and pincer nail deformity were particularly striking. The diagnosis of psoriasis was confirmed by skin biopsy. The eruption resolved after one month of topical momentasone furoate treatment. The role of superantigens in KD-associated psoriasis is discussed.

Original languageEnglish
Article number10
JournalDermatology Online Journal
Volume15
Issue number11
Publication statusPublished - 2009 Nov

Fingerprint

Mucocutaneous Lymph Node Syndrome
Psoriasis
Lip
Cheek
Erythema
Nails
Exanthema
Exfoliative Dermatitis
Skin Manifestations
Systemic Vasculitis
Superantigens
Conjunctiva
Mycobacterium bovis
Pharynx
Foot
Dilatation
Coronary Vessels
Vaccination
Fever
Extremities

All Science Journal Classification (ASJC) codes

  • Dermatology

Cite this

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Psoriasis in a 3-month-old infant with Kawasaki disease. / Liao, Yi Chen; Lee, Yu-Yun.

In: Dermatology Online Journal, Vol. 15, No. 11, 10, 11.2009.

Research output: Contribution to journalArticle

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AB - Kawasaki disease (KD) or mucocutaneous lymph node syndrome is a systemic vasculitis of unknown etiology affecting young children. Typical cutaneous manifestations of KD are polymorphous, including maculopapular or morbilliform rash and erythroderma. Occurrence of psoriasis following KD is rare. Herein we report a case of new onset of psoriasis in a 3-month-old that flared after a typical clinical case of KD, manifesting spiking fever, diffuse redness and fissuring of the lips, bilateral conjunctiva injection, injected throat, left cervical lymphadenopathy, erythema and desquamation of the lips, cheeks, hands, feet and perianal area, and a generalized maculopapular eruption. In addition, erythema and induration of the BCG vaccination site and coronary artery dilatation were noted. After fading of the initial rash, the patient developed widespread psoriasiform papules and plaques involving the face and extremities. The cheeks, lips and nail involvement with subunqual hyperkeratosis and pincer nail deformity were particularly striking. The diagnosis of psoriasis was confirmed by skin biopsy. The eruption resolved after one month of topical momentasone furoate treatment. The role of superantigens in KD-associated psoriasis is discussed.

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