Pulse Oximetry Monitor Feasible for Early Screening of Obstructive Sleep Apnea (OSA)

Huei Chen Lin, Chien Ling Su, Jun Hui Ong, kun ling Tsai, Yu Wen Chen, Cheng-Yu Lin, Ling Ling Chiang, Ching-Hsia Hung

Research output: Contribution to journalArticle

Abstract

Purpose: We postulate that using a simple pulse oximetry monitor (POM) to detect the severity of OSA will help clinical staff confirm the need for early treatment. Hence, we compared the POM-derived oxygen desaturation index (ODI) (events/h) with the polysomnography (PSG)-derived apnea–hypopnea index (AHI) (events/h). Our study is intended to validate the SpO2 measurements and related ODI4% and ODI3% (events/h) calculations from POM associated with AHI and ODI from PSG based on 2007 and 2012 criteria. Methods: All 73 participants (mean age: 51.04 ± 13.14 years old) underwent an overnight PSG test and wore wristwatch POMs (PULSOX 300i) to automatically collect POM oxygen saturation (SpO2) data. Pearson correlation and the Bland and Altman method were used to verify the correlation between POM and PSG. Results: We found that the POM SpO2 and the PSG2007 and PSG2012 scores were significantly highly correlated (total record time [TRT] and lowest SpO2, R2 = 0.815 and 0.817; ODI4%, R2 = 0.912 and 0.863 and ODI3%, R2 = 0.930 and 0.914). AHI was significantly correlated with ODI4% and ODI3%, but ODI3% was nonsignificantly higher (ODI4%, r = 0.955–0.929; ODI3%, r = 0.965–0.956). Both the ODI3% and the ODI4% were highly diagnostically sensitive and specific. The ODI3% score with the AHI 15 events/h cutoff was nonsignificantly higher (area under the curve [AUC] = 0.99, AHI 15 events/h; AUC = 0.95, AHI 5 events/h). Conclusion: We conclude that the ODI3% score is a feasible early screening alternative for patients with moderate-to-severe OSA.

Original languageEnglish
JournalJournal of Medical and Biological Engineering
DOIs
Publication statusPublished - 2019 Jan 1

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Screening
Oxygen
Wear of materials
Sleep

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering

Cite this

Lin, Huei Chen ; Su, Chien Ling ; Ong, Jun Hui ; Tsai, kun ling ; Chen, Yu Wen ; Lin, Cheng-Yu ; Chiang, Ling Ling ; Hung, Ching-Hsia. / Pulse Oximetry Monitor Feasible for Early Screening of Obstructive Sleep Apnea (OSA). In: Journal of Medical and Biological Engineering. 2019.
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abstract = "Purpose: We postulate that using a simple pulse oximetry monitor (POM) to detect the severity of OSA will help clinical staff confirm the need for early treatment. Hence, we compared the POM-derived oxygen desaturation index (ODI) (events/h) with the polysomnography (PSG)-derived apnea–hypopnea index (AHI) (events/h). Our study is intended to validate the SpO2 measurements and related ODI4{\%} and ODI3{\%} (events/h) calculations from POM associated with AHI and ODI from PSG based on 2007 and 2012 criteria. Methods: All 73 participants (mean age: 51.04 ± 13.14 years old) underwent an overnight PSG test and wore wristwatch POMs (PULSOX 300i) to automatically collect POM oxygen saturation (SpO2) data. Pearson correlation and the Bland and Altman method were used to verify the correlation between POM and PSG. Results: We found that the POM SpO2 and the PSG2007 and PSG2012 scores were significantly highly correlated (total record time [TRT] and lowest SpO2, R2 = 0.815 and 0.817; ODI4{\%}, R2 = 0.912 and 0.863 and ODI3{\%}, R2 = 0.930 and 0.914). AHI was significantly correlated with ODI4{\%} and ODI3{\%}, but ODI3{\%} was nonsignificantly higher (ODI4{\%}, r = 0.955–0.929; ODI3{\%}, r = 0.965–0.956). Both the ODI3{\%} and the ODI4{\%} were highly diagnostically sensitive and specific. The ODI3{\%} score with the AHI 15 events/h cutoff was nonsignificantly higher (area under the curve [AUC] = 0.99, AHI 15 events/h; AUC = 0.95, AHI 5 events/h). Conclusion: We conclude that the ODI3{\%} score is a feasible early screening alternative for patients with moderate-to-severe OSA.",
author = "Lin, {Huei Chen} and Su, {Chien Ling} and Ong, {Jun Hui} and Tsai, {kun ling} and Chen, {Yu Wen} and Cheng-Yu Lin and Chiang, {Ling Ling} and Ching-Hsia Hung",
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Pulse Oximetry Monitor Feasible for Early Screening of Obstructive Sleep Apnea (OSA). / Lin, Huei Chen; Su, Chien Ling; Ong, Jun Hui; Tsai, kun ling; Chen, Yu Wen; Lin, Cheng-Yu; Chiang, Ling Ling; Hung, Ching-Hsia.

In: Journal of Medical and Biological Engineering, 01.01.2019.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Pulse Oximetry Monitor Feasible for Early Screening of Obstructive Sleep Apnea (OSA)

AU - Lin, Huei Chen

AU - Su, Chien Ling

AU - Ong, Jun Hui

AU - Tsai, kun ling

AU - Chen, Yu Wen

AU - Lin, Cheng-Yu

AU - Chiang, Ling Ling

AU - Hung, Ching-Hsia

PY - 2019/1/1

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N2 - Purpose: We postulate that using a simple pulse oximetry monitor (POM) to detect the severity of OSA will help clinical staff confirm the need for early treatment. Hence, we compared the POM-derived oxygen desaturation index (ODI) (events/h) with the polysomnography (PSG)-derived apnea–hypopnea index (AHI) (events/h). Our study is intended to validate the SpO2 measurements and related ODI4% and ODI3% (events/h) calculations from POM associated with AHI and ODI from PSG based on 2007 and 2012 criteria. Methods: All 73 participants (mean age: 51.04 ± 13.14 years old) underwent an overnight PSG test and wore wristwatch POMs (PULSOX 300i) to automatically collect POM oxygen saturation (SpO2) data. Pearson correlation and the Bland and Altman method were used to verify the correlation between POM and PSG. Results: We found that the POM SpO2 and the PSG2007 and PSG2012 scores were significantly highly correlated (total record time [TRT] and lowest SpO2, R2 = 0.815 and 0.817; ODI4%, R2 = 0.912 and 0.863 and ODI3%, R2 = 0.930 and 0.914). AHI was significantly correlated with ODI4% and ODI3%, but ODI3% was nonsignificantly higher (ODI4%, r = 0.955–0.929; ODI3%, r = 0.965–0.956). Both the ODI3% and the ODI4% were highly diagnostically sensitive and specific. The ODI3% score with the AHI 15 events/h cutoff was nonsignificantly higher (area under the curve [AUC] = 0.99, AHI 15 events/h; AUC = 0.95, AHI 5 events/h). Conclusion: We conclude that the ODI3% score is a feasible early screening alternative for patients with moderate-to-severe OSA.

AB - Purpose: We postulate that using a simple pulse oximetry monitor (POM) to detect the severity of OSA will help clinical staff confirm the need for early treatment. Hence, we compared the POM-derived oxygen desaturation index (ODI) (events/h) with the polysomnography (PSG)-derived apnea–hypopnea index (AHI) (events/h). Our study is intended to validate the SpO2 measurements and related ODI4% and ODI3% (events/h) calculations from POM associated with AHI and ODI from PSG based on 2007 and 2012 criteria. Methods: All 73 participants (mean age: 51.04 ± 13.14 years old) underwent an overnight PSG test and wore wristwatch POMs (PULSOX 300i) to automatically collect POM oxygen saturation (SpO2) data. Pearson correlation and the Bland and Altman method were used to verify the correlation between POM and PSG. Results: We found that the POM SpO2 and the PSG2007 and PSG2012 scores were significantly highly correlated (total record time [TRT] and lowest SpO2, R2 = 0.815 and 0.817; ODI4%, R2 = 0.912 and 0.863 and ODI3%, R2 = 0.930 and 0.914). AHI was significantly correlated with ODI4% and ODI3%, but ODI3% was nonsignificantly higher (ODI4%, r = 0.955–0.929; ODI3%, r = 0.965–0.956). Both the ODI3% and the ODI4% were highly diagnostically sensitive and specific. The ODI3% score with the AHI 15 events/h cutoff was nonsignificantly higher (area under the curve [AUC] = 0.99, AHI 15 events/h; AUC = 0.95, AHI 5 events/h). Conclusion: We conclude that the ODI3% score is a feasible early screening alternative for patients with moderate-to-severe OSA.

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