Quality of life and sexuality changes in postmenopausal women receiving tibolone therapy

M. H. Wu, H. A. Pan, S. T. Wang, C. C. Hsu, F. M. Chang, K. E. Huang

Research output: Contribution to journalArticlepeer-review

37 Citations (Scopus)

Abstract

Objective: The goal of this study was to investigate the effects of hormone replacement therapy (HRT) and tibolone on the sexuality and quality of life of Taiwanese postmenopausal women. Methods: Forty-eight postmenopausal women were enrolled and prospectively randomized to receive either HRT or tibolone for 3 months. At the end of the 3-month period, quality of life measures were assessed using the Greene Climacteric Scale and attitudes of sexuality were evaluated using the McCoy Sex Scale. Results: Based on subjective qualitative scores, tibolone treatment was at least as effective as continuous combined HRT in improving quality of life. It also effectively prevented withdrawal bleeding, which may occur during HRT use. Compared with continuous combined HRT, tibolone treatment was also associated with perceived improvement of sexual performance, including general sexual satisfaction, sexual interest, sexual fantasies, sexual arousal and orgasm, with decreased frequencies of vaginal dryness and painful intercourse. Conclusions: The findings of this study indicate that both tibolone and continuous combined HRT have positive effects on the quality of life of Taiwanese postmenopausal women. Sexuality is affected more by tibolone than by HRT.

Original languageEnglish
Pages (from-to)314-319
Number of pages6
JournalClimacteric
Volume4
Issue number4
DOIs
Publication statusPublished - 2001 Jan 1

All Science Journal Classification (ASJC) codes

  • Obstetrics and Gynaecology

Fingerprint Dive into the research topics of 'Quality of life and sexuality changes in postmenopausal women receiving tibolone therapy'. Together they form a unique fingerprint.

Cite this