Quantitative spectroscopy of superficial turbid media

Sheng Hao Tseng, Carole Hayakawa, Bruce J. Tromberg, Jerome Spanier, Anthony J. Durkin

Research output: Contribution to journalArticlepeer-review

20 Citations (Scopus)

Abstract

We report a novel diffuse optical spectroscopy probe design for determining optical properties of superficial volumes of turbid samples. The fiber-based probe employs a highly scattering layer placed in contact with the sample of interest. This layer diffuses photons from a collimated light source before they enter the sample and provides a basis for describing light transported in superficial media by the diffusion approximation. We compare the performance of this modified two-layer diffusion model with Monte Carlo simulations. A set of experiments that demonstrate the feasibility of this method in turbid tissue phantoms is also presented. Optical properties deduced by this approach are in good agreement with those derived by use of a benchmark method for determining optical properties. The average interrogation depth of the probe design investigated here is estimated to be less than 1 mm.

Original languageEnglish
Pages (from-to)3165-3167
Number of pages3
JournalOptics Letters
Volume30
Issue number23
DOIs
Publication statusPublished - 2005 Dec 1

All Science Journal Classification (ASJC) codes

  • Atomic and Molecular Physics, and Optics

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