Abstract
In this study, fabrication of microfluidic paper based analytical devices (μPADs) by microembossing was proposed. Different from the embossing methods described in the literature, the filter paper was embossed such that a protruded structure was formed, which subsequently became the channel after heating the wax at the backside of the filter paper. It was found that, when using the Whatman No. 3 filter paper, the embossing pressure needed to be larger than 50 kg/cm2 in conjunction with using a minimal 2-mm wide channel, and the wax heating time ranged from 15 to 45 s in order to obtain a reliable μPAD with repetitive and consistent results. In addition, there was no need of a hydrophobic material as the backside support. The glucose detection was demonstrated using the μPADs as fabricated and a linear relationship was obtained between 5 and 50 mM glucose concentrations. With the proposed method, the processing time of fabricating μPADs can be reduced within approximately 1 min.
| Original language | English |
|---|---|
| Pages (from-to) | 87-92 |
| Number of pages | 6 |
| Journal | Sensors and Actuators, B: Chemical |
| Volume | 283 |
| DOIs | |
| Publication status | Published - 2019 Mar 15 |
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All Science Journal Classification (ASJC) codes
- Electronic, Optical and Magnetic Materials
- Instrumentation
- Condensed Matter Physics
- Surfaces, Coatings and Films
- Metals and Alloys
- Electrical and Electronic Engineering
- Materials Chemistry
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Rapid fabrication of microfluidic paper-based analytical devices by microembossing. / Juang, Yi-Je; Chen, Po Sheng; Wang, Yu.
In: Sensors and Actuators, B: Chemical, Vol. 283, 15.03.2019, p. 87-92.Research output: Contribution to journal › Article
TY - JOUR
T1 - Rapid fabrication of microfluidic paper-based analytical devices by microembossing
AU - Juang, Yi-Je
AU - Chen, Po Sheng
AU - Wang, Yu
PY - 2019/3/15
Y1 - 2019/3/15
N2 - In this study, fabrication of microfluidic paper based analytical devices (μPADs) by microembossing was proposed. Different from the embossing methods described in the literature, the filter paper was embossed such that a protruded structure was formed, which subsequently became the channel after heating the wax at the backside of the filter paper. It was found that, when using the Whatman No. 3 filter paper, the embossing pressure needed to be larger than 50 kg/cm2 in conjunction with using a minimal 2-mm wide channel, and the wax heating time ranged from 15 to 45 s in order to obtain a reliable μPAD with repetitive and consistent results. In addition, there was no need of a hydrophobic material as the backside support. The glucose detection was demonstrated using the μPADs as fabricated and a linear relationship was obtained between 5 and 50 mM glucose concentrations. With the proposed method, the processing time of fabricating μPADs can be reduced within approximately 1 min.
AB - In this study, fabrication of microfluidic paper based analytical devices (μPADs) by microembossing was proposed. Different from the embossing methods described in the literature, the filter paper was embossed such that a protruded structure was formed, which subsequently became the channel after heating the wax at the backside of the filter paper. It was found that, when using the Whatman No. 3 filter paper, the embossing pressure needed to be larger than 50 kg/cm2 in conjunction with using a minimal 2-mm wide channel, and the wax heating time ranged from 15 to 45 s in order to obtain a reliable μPAD with repetitive and consistent results. In addition, there was no need of a hydrophobic material as the backside support. The glucose detection was demonstrated using the μPADs as fabricated and a linear relationship was obtained between 5 and 50 mM glucose concentrations. With the proposed method, the processing time of fabricating μPADs can be reduced within approximately 1 min.
UR - http://www.scopus.com/inward/record.url?scp=85057579413&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85057579413&partnerID=8YFLogxK
U2 - 10.1016/j.snb.2018.12.004
DO - 10.1016/j.snb.2018.12.004
M3 - Article
AN - SCOPUS:85057579413
VL - 283
SP - 87
EP - 92
JO - Sensors and Actuators, B: Chemical
JF - Sensors and Actuators, B: Chemical
SN - 0925-4005
ER -