Rapid Prototyping of an Open-Surface Microfluidic Platform Using Wettability-Patterned Surfaces Prepared by an Atmospheric-Pressure Plasma Jet

She Ting Wu, Chen Yu Huang, Chih Chiang Weng, Chia Chih Chang, Bor Ran Li, Chain Shu Hsu

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Open-surface microfluidics is promising in terms of enabling economical and rapid biochemical analysis for addressing challenges associated with medical diagnosis and food safety. To this end, we present a simple and economical approach to develop an open-surface microfluidic platform suitable for facile liquid transport and mixing. Customizable patterns with tailored wettability are deposited using a plasma-assisted deposition technique under atmospheric pressure. The flow of the dispensed liquid is driven by gravity, and the tilting angle of the device determines the extent of mixing. First, a hexamethyldisiloxane film was deposited to create hydrophobic patterns on glass, and then, hydrophilic acrylic acid was deposited by a patterned cardboard mask to construct a channel suitable for forming channels to transport aqueous liquids without the need of an external energy input; the liquid can be confined to designated pathways. Several designs including Y-junctions, serpentine-shaped patterns, splitting channels, and concentration gradient generation patterns are presented. The proposed method can spatially pattern a surface with a hydrophobic/hydrophilic area, which can function as a microfluidic channel, and the surface can be applied in microfluidic devices with other types of substrates.

Original languageEnglish
Pages (from-to)16292-16299
Number of pages8
JournalACS Omega
Volume4
Issue number15
DOIs
Publication statusPublished - 2019 Oct 8

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Chemical Engineering(all)

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