Background: The aim of this study was to attempt to build a normal chart of fetal biparietal diameter (BPD) based on a pure cross-sectional design with defined normal pregnancy outcome in a Taiwanese population, and to avoid some of the common weaknesses of previously published reports. Materials and Methods: Normal singleton fetuses were enrolled for only one scan between 16 and 41 weeks of gestation in the Antenatal Ultrasound Unit of the National Cheng Kung University Hospital. The data were analyzed by polynomial regression analysis, and the best-fitting equations for the prediction of fetal growth were chosen. By using Altman's method, the standard deviation of each gestational age (GA) was modeled before constructing the fetal growth centile charts. Results: A total of 2,077 fetuses of normal growth were included in the cross-sectional study. The best-fitting equation in the prediction of fetal GA by using the BPD is GA = 0.15912 x BPD + 0.27078 x BPD2 + 13.78204 (R = 0.98107, p < 0.0001). The best-fitting equation in the prediction of fetal BPD by using the GA is BPD = 0.50894 x GA + (-4.49309 x 10-3) x GA2 -3.77477 (R = 0.98133, p < 0.0001). Tables showing BPD growth centiles are generated as a reference chart for prenatal care. Conclusion: After establishing strict criteria of study design and statistical modeling, we believe these fetal BPD values should be more appropriate for evaluation of Taiwanese fetal head growth.
|Number of pages||7|
|Journal||Journal of Medical Ultrasound|
|Publication status||Published - 1996 Jan 1|
All Science Journal Classification (ASJC) codes
- Radiology Nuclear Medicine and imaging