Abstract
The present invention provides a reagent kit of global analysis for protein expression and method for qualitative and quantitative proteomic analysis using the same, characterized in which isotope labeling reagent is utilized to modify enzymatically cleaved peptides in normal or perturbed cells and subsequently tandem mass spectrometry is used to identify protein sequence, and at the same time, accurately measure the protein expression level based on variation in signal intensity.
| Translated title of the contribution | 廣泛性蛋白質質譜分析試劑組及使用該試劑組之蛋白質定性及定量方法 |
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| Original language | English |
| Patent number | 7338806 |
| Publication status | Published - 2005 Mar 24 |