Real time measurement of dopamine releasing under optogenetic stimulation

Cho Han Hsieh, Chun Wei Wu, Meng Chun Liu, Jia Jin Jason Chen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Dopamine (DA) is a neurotransmitter involved in controlling of fine movement, which is deficient in Parkinson’s disease (PD). Measurement of DA is an urgent need concerning the development of PD therapy. We’ve developed a fastscan cyclic voltammetry (FSCV) for real time measurement of dopamine releasing in dopaminergic SH-SY5Y cells under tissue-specific optogenetic stimulation. With the novel cellular optical-induced DA-releasing model, the performance of FSCV will be validated under various stimulating parameters.

Original languageEnglish
Title of host publication1st Global Conference on Biomedical Engineering and 9th Asian-Pacific Conference on Medical and Biological Engineering
EditorsFong-Chin Su, Ming-Long Yeh, Shyh-Hau Wang
PublisherSpringer Verlag
Pages248-250
Number of pages3
ISBN (Electronic)9783319122618
DOIs
Publication statusPublished - 2015
Event1st Global Conference on Biomedical Engineering, GCBME 2014 and 9th Asian-Pacific Conference on Medical and Biological Engineering, APCMBE 2014 - Tainan, Taiwan
Duration: 2014 Oct 92014 Oct 12

Publication series

NameIFMBE Proceedings
Volume47
ISSN (Print)1680-0737
ISSN (Electronic)1433-9277

Other

Other1st Global Conference on Biomedical Engineering, GCBME 2014 and 9th Asian-Pacific Conference on Medical and Biological Engineering, APCMBE 2014
Country/TerritoryTaiwan
CityTainan
Period14-10-0914-10-12

All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Biomedical Engineering

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