Hyaluronan is found in high concentration during embryogenesis and was suggested to play a major role to prevent scar formation in fetal wounds. We have developed a floating collagen gel contraction model to evaluate the effects of hyaluronan. We have found that immersing collagen gels in high concentrations of hyaluronan greatly inhibited the contraction of the gels by fibroblasts.
|Number of pages||6|
|Journal||Biomedical Engineering - Applications, Basis and Communications|
|Publication status||Published - 1993 Jan 1|
All Science Journal Classification (ASJC) codes
- Biomedical Engineering