Reduction of fibroblast contraction on crosslinked hyaluronan-collagen matrices

Lynn Ling-Huei Huang, Marcel E. Nimni

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


Hyaluronan is found in high concentration during embryogenesis and was suggested to play a major role to prevent scar formation in fetal wounds. We have developed a floating collagen gel contraction model to evaluate the effects of hyaluronan. We have found that immersing collagen gels in high concentrations of hyaluronan greatly inhibited the contraction of the gels by fibroblasts.

Original languageEnglish
Pages (from-to)658-663
Number of pages6
JournalBiomedical Engineering - Applications, Basis and Communications
Issue number5
Publication statusPublished - 1993 Jan 1

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Bioengineering
  • Biomedical Engineering


Dive into the research topics of 'Reduction of fibroblast contraction on crosslinked hyaluronan-collagen matrices'. Together they form a unique fingerprint.

Cite this