Regio- and stereo-selectively kinetic resolution of four stereoisomers of 1-phenylbutan-1,3-diol by Candida rugosa lipase

Yi Hui Chen; S. Joly; Pin Mei Huang; Kuang-Sen Sung

doi:10.1139/V06-131

Regio- and stereo-selectively kinetic resolution of four stereoisomers of 1-phenylbutan-1,3-diol by Candida rugosa lipase

Yi Hui Chen, S. Joly, Pin Mei Huang, Kuang-Sen Sung

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

Regio- and stereo-selective Candida rugosa lipase (CRL)-catalyzed acetylations of (±)-syn-1-phenylbutan-1,3-diols ((±)-syn-1) generated two monoacetates, (+)-syn-2 and (-)-syn-3, whereas that of (±)-anti-1 produced a monoacetate, (+)-anti-3, and an unreacted (-)-anti-1.

Original language	English
Pages (from-to)	1031-1035
Number of pages	5
Journal	Canadian Journal of Chemistry
Volume	84
Issue number	8
DOIs	https://doi.org/10.1139/V06-131
Publication status	Published - 2006 Aug 1

All Science Journal Classification (ASJC) codes

Catalysis
Chemistry(all)
Organic Chemistry

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abstract = "Regio- and stereo-selective Candida rugosa lipase (CRL)-catalyzed acetylations of (±)-syn-1-phenylbutan-1,3-diols ((±)-syn-1) generated two monoacetates, (+)-syn-2 and (-)-syn-3, whereas that of (±)-anti-1 produced a monoacetate, (+)-anti-3, and an unreacted (-)-anti-1.",

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AU - Sung, Kuang-Sen

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