Registration-based segmentation of nerve cells in microscopy images

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Nerve cell segmentation is important for better understanding of the connections between broken nerves. In this paper, we propose a registration-based segmentation to improve the segmentation from a series of microscopic image sequence. A global iterative closest point (ICP) registration is first employed to find the corresponding cells between neighboring frames. Then a local ICP registration is adopted to refine shape matching between corresponding cells. When registering the current frame to the previous frame, a missing cell in the current frame can obtain a dummy region with respect to the previous frame. The dummy region is then confirmed as a cell by checking the correspondence of the cell among the previous, current and next frames. Experimental results show that the proposed registration based algorithm recovers the cells that are missed in conventional segmentation.

Original languageEnglish
Title of host publicationProceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Subtitle of host publicationEngineering the Future of Biomedicine, EMBC 2009
PublisherIEEE Computer Society
Pages6726-6729
Number of pages4
ISBN (Print)9781424432967
DOIs
Publication statusPublished - 2009 Jan 1
Event31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009 - Minneapolis, MN, United States
Duration: 2009 Sep 22009 Sep 6

Publication series

NameProceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009

Other

Other31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009
CountryUnited States
CityMinneapolis, MN
Period09-09-0209-09-06

All Science Journal Classification (ASJC) codes

  • Cell Biology
  • Developmental Biology
  • Biomedical Engineering
  • Medicine(all)

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