Reliability analysis of physiological phenomena by cardiac action potential model

Ching Hsing Luo, Po Yuan Chen, Chun Hao Teng, Sheng-Nan Wu, Ruey Jen Sung

Research output: Contribution to journalConference article

Abstract

To simulate ventricular cardiac action potentials used Luo-Rudy phase I cell model with hybrid method, the computation time can be 100 times faster than RK4 (fixed step 0.01); However, the hybrid method of time step 0.8-2.0 causes the irregular S:R ratio by Wenckebach periodicity as stimulation 30 beats; other hybrid methods can adequately simulate cardiac physiology phenomena and prevent from phantom simulation. In this study, we analysis the simulation reliability and accuracy for three different speeds of hybrid methods that compare to RK4 (0.01), thus a suggestion can be understood how to select the right methods to simulate the physiological phenomena under computing speed fast enough and maintain the accuracy, saving huge amount of the computing time in the cardiac simulations.

Original languageEnglish
Article number4253282
Pages (from-to)2890-2893
Number of pages4
JournalProceedings - IEEE International Symposium on Circuits and Systems
Publication statusPublished - 2007 Sep 27
Event2007 IEEE International Symposium on Circuits and Systems, ISCAS 2007 - New Orleans, LA, United States
Duration: 2007 May 272007 May 30

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Reliability analysis
Physiology

All Science Journal Classification (ASJC) codes

  • Electrical and Electronic Engineering

Cite this

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title = "Reliability analysis of physiological phenomena by cardiac action potential model",
abstract = "To simulate ventricular cardiac action potentials used Luo-Rudy phase I cell model with hybrid method, the computation time can be 100 times faster than RK4 (fixed step 0.01); However, the hybrid method of time step 0.8-2.0 causes the irregular S:R ratio by Wenckebach periodicity as stimulation 30 beats; other hybrid methods can adequately simulate cardiac physiology phenomena and prevent from phantom simulation. In this study, we analysis the simulation reliability and accuracy for three different speeds of hybrid methods that compare to RK4 (0.01), thus a suggestion can be understood how to select the right methods to simulate the physiological phenomena under computing speed fast enough and maintain the accuracy, saving huge amount of the computing time in the cardiac simulations.",
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Reliability analysis of physiological phenomena by cardiac action potential model. / Luo, Ching Hsing; Chen, Po Yuan; Teng, Chun Hao; Wu, Sheng-Nan; Sung, Ruey Jen.

In: Proceedings - IEEE International Symposium on Circuits and Systems, 27.09.2007, p. 2890-2893.

Research output: Contribution to journalConference article

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T1 - Reliability analysis of physiological phenomena by cardiac action potential model

AU - Luo, Ching Hsing

AU - Chen, Po Yuan

AU - Teng, Chun Hao

AU - Wu, Sheng-Nan

AU - Sung, Ruey Jen

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