Review: Application of nanoparticles in urothelial cancer of the urinary bladder

Chieh Hsiao Chen, Tzu Min Chan, Yi Jhen Wu, Jia Jin Chen

Research output: Contribution to journalReview articlepeer-review

16 Citations (Scopus)


Bladder cancer is a common malignancy of the urinary tract, which generally develops in the epithelial lining of the urinary bladder. The specific course of treatment depends on the stage of bladder cancer; however, therapeutic strategies typically involve intravesical drug delivery to reduce toxicity and increase therapeutic effects. Recently, metallic, polymeric, lipid, and protein nanoparticles have been introduced to aid in the treatment of bladder cancer. Nanoparticles are also commonly used as pharmaceutical carriers to improve interactions between drugs and the urothelium. In this review, we classify the characteristics of bladder cancer and discuss the types of nanoparticles used in various treatment modalities. Finallywe summarize the potential applications and benefits of various nanoparticles in intravesical therapy.

Original languageEnglish
Pages (from-to)419-427
Number of pages9
JournalJournal of Medical and Biological Engineering
Issue number4
Publication statusPublished - 2015 Aug

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering


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