TY - JOUR
T1 - Rigorous quantitative sciences integration-the foundation of high-dimensional genomic research
AU - Shyr, Yu
PY - 2012/10
Y1 - 2012/10
N2 - With the recent rapid increases in the highdimensionality of genomic data generation comes an increased burden on the biostatisticians and bioinformaticians who process and analyze this data. Study designs must be adapted to the volume of data now available, eliminating designs that rely on fishing and taking advantage of the massive amounts of publically available genomic data through data-mining. Most importantly, it is no longer sufficient to have a single person handling the data analysis. To get the breadth of expertise needed to analyze high-dimensional data and to have the appropriate checks to eliminate the costly mistakes that are so easy to make when handling this volume of data, specialists from many different areas of quantitative sciences must be brought together to approach high-dimensional data analysis as an integrated team.
AB - With the recent rapid increases in the highdimensionality of genomic data generation comes an increased burden on the biostatisticians and bioinformaticians who process and analyze this data. Study designs must be adapted to the volume of data now available, eliminating designs that rely on fishing and taking advantage of the massive amounts of publically available genomic data through data-mining. Most importantly, it is no longer sufficient to have a single person handling the data analysis. To get the breadth of expertise needed to analyze high-dimensional data and to have the appropriate checks to eliminate the costly mistakes that are so easy to make when handling this volume of data, specialists from many different areas of quantitative sciences must be brought together to approach high-dimensional data analysis as an integrated team.
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U2 - 10.1007/s10585-012-9508-y
DO - 10.1007/s10585-012-9508-y
M3 - Article
C2 - 22798219
AN - SCOPUS:84868198137
SN - 0262-0898
VL - 29
SP - 641
EP - 643
JO - Clinical and Experimental Metastasis
JF - Clinical and Experimental Metastasis
IS - 7
ER -