Abstract
OBJECTIVE - We prospectively assessed the age- and sex-specific incidence and relative risk of malignant neoplasm of the pancreas in Taiwan's diabetic population. RESEARCH DESIGN AND METHODS - A total of 615,532 diabetic patients and 614,871 age- and sex-matched control subjects were linked to inpatient claims (2000-2006) to identify the admissions for malignant neoplasm of the pancreas (ICD-9: 157). The Cox proportional hazards regression model was used to estimate the age- and sex-specific relative risk of pancreatic neoplasm. RESULTS - Compared with the control group, the diabetic patients had a significantly increased risk of pancreatic cancer (hazard ratio [HR] 1.54 [95% CI 1.39-1.71]). The higher and significant age-specific HRs were observed in diabetic men (1.91) and women (1.80) aged 45-65 years. CONCLUSIONS - Middle-aged diabetic men and women were associated with the most increased risk of malignant neoplasm of the pancreas.
Original language | English |
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Pages (from-to) | 1177-1179 |
Number of pages | 3 |
Journal | Diabetes Care |
Volume | 34 |
Issue number | 5 |
DOIs | |
Publication status | Published - 2011 May |
All Science Journal Classification (ASJC) codes
- Internal Medicine
- Endocrinology, Diabetes and Metabolism
- Advanced and Specialised Nursing