Abstract
The present invention relates to an RNAi compound and an expression plasmid for inhibiting expression of Thrombospondin-1, which comprises a target sequence selected from Thrombospondin-1 gene. The present invention also related to a pharmaceutical composition comprising the RNAi compound and applications thereof. The RNAi compound can reduce the expression of Thrombospondin-1 to activate immune responses.
| Translated title of the contribution | 第一型血小板活化素siRNA分子及其應用 |
|---|---|
| Original language | English |
| Patent number | 8377902 |
| Publication status | Published - 2011 Jul 7 |