RNAi compound targeted to thrombospondin-1 and applications thereof

Ming-Derg Lai (Inventor)

Research output: Patent


The present invention relates to an RNAi compound and an expression plasmid for inhibiting expression of Thrombospondin-1, which comprises a target sequence selected from Thrombospondin-1 gene. The present invention also related to a pharmaceutical composition comprising the RNAi compound and applications thereof. The RNAi compound can reduce the expression of Thrombospondin-1 to activate immune responses.
Translated title of the contribution第一型血小板活化素siRNA分子及其應用
Original languageEnglish
Patent number8377902
Publication statusPublished - 2011 Jul 7


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