Robust and brilliant Raman tags based on core-satellite assemblies for brain tumor cell imaging

Yung Ching Chang; Li Ching Huang; Wei Lun Sun; Shih Yi Chuang; Tien Hsin Lin; Yi Syuan Wu; Chun I. Sze; Shiuan Yeh Chen

doi:10.1117/12.2290194

Robust and brilliant Raman tags based on core-satellite assemblies for brain tumor cell imaging

Yung Ching Chang, Li Ching Huang, Wei Lun Sun, Shih Yi Chuang, Tien Hsin Lin, Yi Syuan Wu, Chun I. Sze, Shiuan Yeh Chen

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

GBM (Glioblastoma Multiforme), a fatal brain tumor, is highly infiltrative and difficult to be completely removed by the surgery. In this work, the Raman tags based on the plasmonic core-satellite assemblies with ∼1 nm internal gap accompanied by extremely high gap field have been fabricated and applied to GBM cell labeling. The brightness of the Raman tags is comparable to the fluorophores. The GBM cells with overexpression of EGFR are labeled with these Raman tags and can be distinguished from the normal cells through Raman imaging.

Original language	English
Title of host publication	Biomedical Vibrational Spectroscopy 2018
Subtitle of host publication	Advances in Research and Industry
Editors	Anita Mahadevan-Jansen, Wolfgang Petrich
Publisher	SPIE
ISBN (Electronic)	9781510614659
DOIs	https://doi.org/10.1117/12.2290194
Publication status	Published - 2018
Event	Biomedical Vibrational Spectroscopy 2018: Advances in Research and Industry - San Francisco, United States Duration: 2018 Jan 27 → 2018 Jan 28

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	10490
ISSN (Print)	1605-7422

Other

Other	Biomedical Vibrational Spectroscopy 2018: Advances in Research and Industry
Country/Territory	United States
City	San Francisco
Period	18-01-27 → 18-01-28

All Science Journal Classification (ASJC) codes

Electronic, Optical and Magnetic Materials
Atomic and Molecular Physics, and Optics
Radiology Nuclear Medicine and imaging
Biomaterials

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10.1117/12.2290194

Cite this

Chang, Y. C., Huang, L. C., Sun, W. L., Chuang, S. Y., Lin, T. H., Wu, Y. S., Sze, C. I., & Chen, S. Y. (2018). Robust and brilliant Raman tags based on core-satellite assemblies for brain tumor cell imaging. In A. Mahadevan-Jansen, & W. Petrich (Eds.), Biomedical Vibrational Spectroscopy 2018: Advances in Research and Industry Article 1049006 (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10490). SPIE. https://doi.org/10.1117/12.2290194

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title = "Robust and brilliant Raman tags based on core-satellite assemblies for brain tumor cell imaging",

abstract = "GBM (Glioblastoma Multiforme), a fatal brain tumor, is highly infiltrative and difficult to be completely removed by the surgery. In this work, the Raman tags based on the plasmonic core-satellite assemblies with ∼1 nm internal gap accompanied by extremely high gap field have been fabricated and applied to GBM cell labeling. The brightness of the Raman tags is comparable to the fluorophores. The GBM cells with overexpression of EGFR are labeled with these Raman tags and can be distinguished from the normal cells through Raman imaging.",

author = "Chang, {Yung Ching} and Huang, {Li Ching} and Sun, {Wei Lun} and Chuang, {Shih Yi} and Lin, {Tien Hsin} and Wu, {Yi Syuan} and Sze, {Chun I.} and Chen, {Shiuan Yeh}",

note = "Publisher Copyright: {\textcopyright} 2018 SPIE.; Biomedical Vibrational Spectroscopy 2018: Advances in Research and Industry ; Conference date: 27-01-2018 Through 28-01-2018",

year = "2018",

doi = "10.1117/12.2290194",

language = "English",

series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

publisher = "SPIE",

editor = "Anita Mahadevan-Jansen and Wolfgang Petrich",

booktitle = "Biomedical Vibrational Spectroscopy 2018",

address = "United States",

}

Chang, YC, Huang, LC, Sun, WL, Chuang, SY, Lin, TH, Wu, YS, Sze, CI & Chen, SY 2018, Robust and brilliant Raman tags based on core-satellite assemblies for brain tumor cell imaging. in A Mahadevan-Jansen & W Petrich (eds), Biomedical Vibrational Spectroscopy 2018: Advances in Research and Industry., 1049006, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 10490, SPIE, Biomedical Vibrational Spectroscopy 2018: Advances in Research and Industry, San Francisco, United States, 18-01-27. https://doi.org/10.1117/12.2290194

Robust and brilliant Raman tags based on core-satellite assemblies for brain tumor cell imaging. / Chang, Yung Ching; Huang, Li Ching; Sun, Wei Lun et al.
Biomedical Vibrational Spectroscopy 2018: Advances in Research and Industry. ed. / Anita Mahadevan-Jansen; Wolfgang Petrich. SPIE, 2018. 1049006 (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10490).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

TY - GEN

T1 - Robust and brilliant Raman tags based on core-satellite assemblies for brain tumor cell imaging

AU - Chang, Yung Ching

AU - Huang, Li Ching

AU - Sun, Wei Lun

AU - Chuang, Shih Yi

AU - Lin, Tien Hsin

AU - Wu, Yi Syuan

AU - Sze, Chun I.

AU - Chen, Shiuan Yeh

PY - 2018

Y1 - 2018

N2 - GBM (Glioblastoma Multiforme), a fatal brain tumor, is highly infiltrative and difficult to be completely removed by the surgery. In this work, the Raman tags based on the plasmonic core-satellite assemblies with ∼1 nm internal gap accompanied by extremely high gap field have been fabricated and applied to GBM cell labeling. The brightness of the Raman tags is comparable to the fluorophores. The GBM cells with overexpression of EGFR are labeled with these Raman tags and can be distinguished from the normal cells through Raman imaging.

AB - GBM (Glioblastoma Multiforme), a fatal brain tumor, is highly infiltrative and difficult to be completely removed by the surgery. In this work, the Raman tags based on the plasmonic core-satellite assemblies with ∼1 nm internal gap accompanied by extremely high gap field have been fabricated and applied to GBM cell labeling. The brightness of the Raman tags is comparable to the fluorophores. The GBM cells with overexpression of EGFR are labeled with these Raman tags and can be distinguished from the normal cells through Raman imaging.

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M3 - Conference contribution

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T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

BT - Biomedical Vibrational Spectroscopy 2018

A2 - Mahadevan-Jansen, Anita

A2 - Petrich, Wolfgang

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T2 - Biomedical Vibrational Spectroscopy 2018: Advances in Research and Industry

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Chang YC, Huang LC, Sun WL, Chuang SY, Lin TH, Wu YS et al. Robust and brilliant Raman tags based on core-satellite assemblies for brain tumor cell imaging. In Mahadevan-Jansen A, Petrich W, editors, Biomedical Vibrational Spectroscopy 2018: Advances in Research and Industry. SPIE. 2018. 1049006. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE). doi: 10.1117/12.2290194

Robust and brilliant Raman tags based on core-satellite assemblies for brain tumor cell imaging

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