Role of glycosylation in vascular calcification

Ainun Nizar Masbuchin, Mohammad Saifur Rohman, Ping Yen Liu

Research output: Contribution to journalReview articlepeer-review

10 Citations (Scopus)

Abstract

Glycosylation is an important step in post-translational protein modification. Altered glycosylation results in an abnormality that causes diseases such as malignancy and cardiovascular diseases. Recent emerging evidence highlights the importance of glycosylation in vascular calcification. Two major types of glycosylation, N-glycosylation and O-glycosylation, are involved in vascular calcification. Other glycosylation mechanisms, which polymerize the glycosaminoglycan (GAG) chain onto protein, resulting in proteoglycan (PG), also have an impact on vascular calcification. This paper discusses the role of glycosylation in vascular calcification.

Original languageEnglish
Article number9829
JournalInternational journal of molecular sciences
Volume22
Issue number18
DOIs
Publication statusPublished - 2021 Sept

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Molecular Biology
  • Spectroscopy
  • Computer Science Applications
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

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