Saturated saline enhances the effect of electrochemical therapy

Xi Zhang Lin, Chung Min Jen, Chao Kai Chou, Chao Shan Chou, Ming Je Sung, Tse Chuan Chou

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)


We conducted this experiment to assess the effect of saline injection in electrochemical therapy. Platinum electrodes using direct current were inserted into egg white or liver parenchyma. Pure water or 0.9%, 3%, or 26% sodium chloride were injected into various objects to compare with the control group (no injection). Power was set at 10 V. In the egg-white experiment, gas bubbles and coagulated protein developed around the electrodes. In ex vivo liver, frothy reddish debris developed around the cathodes, while a hardening and shrunken surface occurred around the anodes. The pH was 14 around the cathodes, 0 around the anodes. The electric current, the amount of coagulated protein, and the severity of tissue damage were all in proportion to the concentrations of the injected saline. The volume destroyed in the 26% saline group was 8.1 times larger than that of the control group. Therefore, injected saline, especially saturated saline, can enhance the effect of electrochemical therapy.

Original languageEnglish
Pages (from-to)509-514
Number of pages6
JournalDigestive Diseases and Sciences
Issue number3
Publication statusPublished - 2000

All Science Journal Classification (ASJC) codes

  • Physiology
  • Gastroenterology


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