Scanned laser pico-projection image processing for cancer-like cells induced by isopropyl β-D-1-thiogalactopyranoside

Yi Hsuan Wu, Wen Tai Chiu, Meng Jia Lian, Chih Ling Huang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Compared to normal cells, cancer cells have unique characteristic in oncogene and morphology. Isopropyl β-D-1-thiogalactopyranoside (IPTG) can be used as an inducer to trigger transcription of oncogene Ha-ras. Scanned Laser Pico-Projection (SLPP) image provide a texture enhancement effect for analyzing features of cell morphology. In this study, we also use Gray-level Co-occurrence Matrix (GLCM), a common method for image processing, to analyze to morphology texture. The cancer-like cells (MK4 and 7-4 cells) induced by IPTG from normal cells (MDCK and NIH-3T3) have the higher Contrast and Entropy, but the lower Correlation, Homogeneity, and Energy. It can differentiate normal & cancer-like pairs and works on epithelial and fibroblast cells. It means that it can classify the major cell species of cancer occurrence.

Original languageEnglish
Title of host publicationICBET 2018 - Proceedings of 2018 8th International Conference on Biomedical Engineering and Technology
PublisherAssociation for Computing Machinery
Pages61-64
Number of pages4
ISBN (Electronic)9781450363693
DOIs
Publication statusPublished - 2018 Apr 23
Event8th International Conference on Biomedical Engineering and Technology, ICBET 2018 - Bali, Indonesia
Duration: 2018 Apr 232018 Apr 25

Publication series

NameACM International Conference Proceeding Series

Conference

Conference8th International Conference on Biomedical Engineering and Technology, ICBET 2018
CountryIndonesia
CityBali
Period18-04-2318-04-25

All Science Journal Classification (ASJC) codes

  • Software
  • Human-Computer Interaction
  • Computer Vision and Pattern Recognition
  • Computer Networks and Communications

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    Wu, Y. H., Chiu, W. T., Lian, M. J., & Huang, C. L. (2018). Scanned laser pico-projection image processing for cancer-like cells induced by isopropyl β-D-1-thiogalactopyranoside. In ICBET 2018 - Proceedings of 2018 8th International Conference on Biomedical Engineering and Technology (pp. 61-64). (ACM International Conference Proceeding Series). Association for Computing Machinery. https://doi.org/10.1145/3208955.3208973