Scanned laser pico-projection image processing for cancer-like cells induced by isopropyl β-D-1-thiogalactopyranoside

Yi Hsuan Wu; Wen Tai Chiu; Meng Jia Lian; Chih Ling Huang

doi:10.1145/3208955.3208973

Scanned laser pico-projection image processing for cancer-like cells induced by isopropyl β-D-1-thiogalactopyranoside

Yi Hsuan Wu, Wen Tai Chiu, Meng Jia Lian, Chih Ling Huang

Department of Biomedical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Compared to normal cells, cancer cells have unique characteristic in oncogene and morphology. Isopropyl β-D-1-thiogalactopyranoside (IPTG) can be used as an inducer to trigger transcription of oncogene Ha-ras. Scanned Laser Pico-Projection (SLPP) image provide a texture enhancement effect for analyzing features of cell morphology. In this study, we also use Gray-level Co-occurrence Matrix (GLCM), a common method for image processing, to analyze to morphology texture. The cancer-like cells (MK4 and 7-4 cells) induced by IPTG from normal cells (MDCK and NIH-3T3) have the higher Contrast and Entropy, but the lower Correlation, Homogeneity, and Energy. It can differentiate normal & cancer-like pairs and works on epithelial and fibroblast cells. It means that it can classify the major cell species of cancer occurrence.

Original language	English
Title of host publication	ICBET 2018 - Proceedings of 2018 8th International Conference on Biomedical Engineering and Technology
Publisher	Association for Computing Machinery
Pages	61-64
Number of pages	4
ISBN (Electronic)	9781450363693
DOIs	https://doi.org/10.1145/3208955.3208973
Publication status	Published - 2018 Apr 23
Event	8th International Conference on Biomedical Engineering and Technology, ICBET 2018 - Bali, Indonesia Duration: 2018 Apr 23 → 2018 Apr 25

Publication series

Name	ACM International Conference Proceeding Series

Conference

Conference	8th International Conference on Biomedical Engineering and Technology, ICBET 2018
Country	Indonesia
City	Bali
Period	18-04-23 → 18-04-25

All Science Journal Classification (ASJC) codes

Software
Human-Computer Interaction
Computer Vision and Pattern Recognition
Computer Networks and Communications

Access to Document

10.1145/3208955.3208973

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Wu, Y. H., Chiu, W. T., Lian, M. J., & Huang, C. L. (2018). Scanned laser pico-projection image processing for cancer-like cells induced by isopropyl β-D-1-thiogalactopyranoside. In ICBET 2018 - Proceedings of 2018 8th International Conference on Biomedical Engineering and Technology (pp. 61-64). (ACM International Conference Proceeding Series). Association for Computing Machinery. https://doi.org/10.1145/3208955.3208973

Wu, Yi Hsuan ; Chiu, Wen Tai ; Lian, Meng Jia ; Huang, Chih Ling. / Scanned laser pico-projection image processing for cancer-like cells induced by isopropyl β-D-1-thiogalactopyranoside. ICBET 2018 - Proceedings of 2018 8th International Conference on Biomedical Engineering and Technology. Association for Computing Machinery, 2018. pp. 61-64 (ACM International Conference Proceeding Series).

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title = "Scanned laser pico-projection image processing for cancer-like cells induced by isopropyl β-D-1-thiogalactopyranoside",

abstract = "Compared to normal cells, cancer cells have unique characteristic in oncogene and morphology. Isopropyl β-D-1-thiogalactopyranoside (IPTG) can be used as an inducer to trigger transcription of oncogene Ha-ras. Scanned Laser Pico-Projection (SLPP) image provide a texture enhancement effect for analyzing features of cell morphology. In this study, we also use Gray-level Co-occurrence Matrix (GLCM), a common method for image processing, to analyze to morphology texture. The cancer-like cells (MK4 and 7-4 cells) induced by IPTG from normal cells (MDCK and NIH-3T3) have the higher Contrast and Entropy, but the lower Correlation, Homogeneity, and Energy. It can differentiate normal & cancer-like pairs and works on epithelial and fibroblast cells. It means that it can classify the major cell species of cancer occurrence.",

author = "Wu, {Yi Hsuan} and Chiu, {Wen Tai} and Lian, {Meng Jia} and Huang, {Chih Ling}",

year = "2018",

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doi = "10.1145/3208955.3208973",

language = "English",

series = "ACM International Conference Proceeding Series",

publisher = "Association for Computing Machinery",

pages = "61--64",

booktitle = "ICBET 2018 - Proceedings of 2018 8th International Conference on Biomedical Engineering and Technology",

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Wu, YH, Chiu, WT, Lian, MJ & Huang, CL 2018, Scanned laser pico-projection image processing for cancer-like cells induced by isopropyl β-D-1-thiogalactopyranoside. in ICBET 2018 - Proceedings of 2018 8th International Conference on Biomedical Engineering and Technology. ACM International Conference Proceeding Series, Association for Computing Machinery, pp. 61-64, 8th International Conference on Biomedical Engineering and Technology, ICBET 2018, Bali, Indonesia, 18-04-23. https://doi.org/10.1145/3208955.3208973

Scanned laser pico-projection image processing for cancer-like cells induced by isopropyl β-D-1-thiogalactopyranoside. / Wu, Yi Hsuan; Chiu, Wen Tai; Lian, Meng Jia; Huang, Chih Ling.

ICBET 2018 - Proceedings of 2018 8th International Conference on Biomedical Engineering and Technology. Association for Computing Machinery, 2018. p. 61-64 (ACM International Conference Proceeding Series).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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Wu YH, Chiu WT, Lian MJ, Huang CL. Scanned laser pico-projection image processing for cancer-like cells induced by isopropyl β-D-1-thiogalactopyranoside. In ICBET 2018 - Proceedings of 2018 8th International Conference on Biomedical Engineering and Technology. Association for Computing Machinery. 2018. p. 61-64. (ACM International Conference Proceeding Series). https://doi.org/10.1145/3208955.3208973