TY - GEN
T1 - Scanned laser pico-projection image processing for cancer-like cells induced by isopropyl β-D-1-thiogalactopyranoside
AU - Wu, Yi Hsuan
AU - Chiu, Wen Tai
AU - Lian, Meng Jia
AU - Huang, Chih Ling
N1 - Funding Information:
The authors gratefully acknowledge the financial support provided to this study by the Ministry of Science and Technology (MOST) in Taiwan under Grant Nos. MOST-106-2221-E-037 - 004. Supported by a grant from the Kaohsiung Medical University Research Foundation (KMU-Q106007).
Funding Information:
The authors gratefully acknowledge the financial support provided to this study by the Ministry of Science and Technology (MOST) in Taiwan under Grant Nos. MOST- 106-2221-E-037 - 004. Supported by a grant from the Kaohsiung Medical University Research Foundation (KMU-Q106007).
Publisher Copyright:
© 2018 Association for Computing Machinery.
PY - 2018/4/23
Y1 - 2018/4/23
N2 - Compared to normal cells, cancer cells have unique characteristic in oncogene and morphology. Isopropyl β-D-1-thiogalactopyranoside (IPTG) can be used as an inducer to trigger transcription of oncogene Ha-ras. Scanned Laser Pico-Projection (SLPP) image provide a texture enhancement effect for analyzing features of cell morphology. In this study, we also use Gray-level Co-occurrence Matrix (GLCM), a common method for image processing, to analyze to morphology texture. The cancer-like cells (MK4 and 7-4 cells) induced by IPTG from normal cells (MDCK and NIH-3T3) have the higher Contrast and Entropy, but the lower Correlation, Homogeneity, and Energy. It can differentiate normal & cancer-like pairs and works on epithelial and fibroblast cells. It means that it can classify the major cell species of cancer occurrence.
AB - Compared to normal cells, cancer cells have unique characteristic in oncogene and morphology. Isopropyl β-D-1-thiogalactopyranoside (IPTG) can be used as an inducer to trigger transcription of oncogene Ha-ras. Scanned Laser Pico-Projection (SLPP) image provide a texture enhancement effect for analyzing features of cell morphology. In this study, we also use Gray-level Co-occurrence Matrix (GLCM), a common method for image processing, to analyze to morphology texture. The cancer-like cells (MK4 and 7-4 cells) induced by IPTG from normal cells (MDCK and NIH-3T3) have the higher Contrast and Entropy, but the lower Correlation, Homogeneity, and Energy. It can differentiate normal & cancer-like pairs and works on epithelial and fibroblast cells. It means that it can classify the major cell species of cancer occurrence.
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U2 - 10.1145/3208955.3208973
DO - 10.1145/3208955.3208973
M3 - Conference contribution
AN - SCOPUS:85055513109
T3 - ACM International Conference Proceeding Series
SP - 61
EP - 64
BT - ICBET 2018 - Proceedings of 2018 8th International Conference on Biomedical Engineering and Technology
PB - Association for Computing Machinery
T2 - 8th International Conference on Biomedical Engineering and Technology, ICBET 2018
Y2 - 23 April 2018 through 25 April 2018
ER -