Scrub typhus associated with multiorgan failure: A case report

Wen Che Chi, Jeng Jong Huang, Junne Ming Sung, Rong Rue Lan, Wen Chien Ko, Fen Fen Chen

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54 Citations (Scopus)


The spectrum of clinical severity for scrub typhus ranges from inapparent, mild, to severe or fatal. The pathologic changes are focal or disseminated multiorgan vasculitis of the small blood vessels, a fact that helps explain the great diversity of clinical manifestations that can be encountered. We reported a case of scrub typhus with unusual and serious multiorgan involvement, including tubulointerstitial nephritis (TIN) with acute renal failure (ARF), interstitial pneumonitis with adult respiratory distress syndrome (ARDS), disseminated intravascular coagulation (DIC), liver function impairment, upper gastrointestinal bleeding, prolonged hyperamylasaemia and hyperlipasaemia. Chloramphenicol administration rapidly altered the clinical course, but with sequelae of renal impairment and prolonged hyperamylasaemia and hyperlipasaemia for 10 months.

Original languageEnglish
Pages (from-to)634-635
Number of pages2
JournalScandinavian Journal of Infectious Diseases
Issue number6
Publication statusPublished - 1997

All Science Journal Classification (ASJC) codes

  • Immunology and Microbiology(all)
  • Microbiology (medical)
  • Infectious Diseases

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