Sesame seed (sesamum indicum l.) extracts and their anti-inflammatory effect

Dur Zong Hsu, Pei Yi Chu, Ming Yie Liu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Citations (Scopus)

Abstract

Steroids and non-steroidal anti-inflammatory drugs (NSAIDs) are the main choices for controlling inflammation. However, their adverse effects limit their clinical use. Sesame (Sesamum indicum L.) is one of the oldest cultivated plants in the world. Its extracts, such as sesame oil, have been widely used since ancient times. Recently, sesame oil and its lignan sesamol have been proved to be potent anti-inflammatory agents. They have an excellent protective effect against endotoxin-associated inflammatory damage because they inhibit the release of inflammatory mediators. Sesamol also inhibits endotoxins from binding to its receptor; this reduces inflammatory transcription factor NF-?B activation. In summary, sesame oil or sesamol may be beneficial for reducing the inflammatory response in inflammation-associated diseases.

Original languageEnglish
Title of host publicationEmerging Trends in Dietary Components for Preventing and Combating Disease
PublisherAmerican Chemical Society
Pages335-341
Number of pages7
ISBN (Print)9780841226647
DOIs
Publication statusPublished - 2012 Jan 1

Publication series

NameACS Symposium Series
Volume1093
ISSN (Print)0097-6156
ISSN (Electronic)1947-5918

Fingerprint

Sesame Oil
Seed
Anti-Inflammatory Agents
Endotoxins
Lignans
Transcription factors
Transcription Factors
Chemical activation
Steroids
Pharmaceutical Preparations
sesamol
Oils

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Chemical Engineering(all)

Cite this

Hsu, D. Z., Chu, P. Y., & Liu, M. Y. (2012). Sesame seed (sesamum indicum l.) extracts and their anti-inflammatory effect. In Emerging Trends in Dietary Components for Preventing and Combating Disease (pp. 335-341). (ACS Symposium Series; Vol. 1093). American Chemical Society. https://doi.org/10.1021/bk-2012-1093.ch019
Hsu, Dur Zong ; Chu, Pei Yi ; Liu, Ming Yie. / Sesame seed (sesamum indicum l.) extracts and their anti-inflammatory effect. Emerging Trends in Dietary Components for Preventing and Combating Disease. American Chemical Society, 2012. pp. 335-341 (ACS Symposium Series).
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Hsu, DZ, Chu, PY & Liu, MY 2012, Sesame seed (sesamum indicum l.) extracts and their anti-inflammatory effect. in Emerging Trends in Dietary Components for Preventing and Combating Disease. ACS Symposium Series, vol. 1093, American Chemical Society, pp. 335-341. https://doi.org/10.1021/bk-2012-1093.ch019

Sesame seed (sesamum indicum l.) extracts and their anti-inflammatory effect. / Hsu, Dur Zong; Chu, Pei Yi; Liu, Ming Yie.

Emerging Trends in Dietary Components for Preventing and Combating Disease. American Chemical Society, 2012. p. 335-341 (ACS Symposium Series; Vol. 1093).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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N2 - Steroids and non-steroidal anti-inflammatory drugs (NSAIDs) are the main choices for controlling inflammation. However, their adverse effects limit their clinical use. Sesame (Sesamum indicum L.) is one of the oldest cultivated plants in the world. Its extracts, such as sesame oil, have been widely used since ancient times. Recently, sesame oil and its lignan sesamol have been proved to be potent anti-inflammatory agents. They have an excellent protective effect against endotoxin-associated inflammatory damage because they inhibit the release of inflammatory mediators. Sesamol also inhibits endotoxins from binding to its receptor; this reduces inflammatory transcription factor NF-?B activation. In summary, sesame oil or sesamol may be beneficial for reducing the inflammatory response in inflammation-associated diseases.

AB - Steroids and non-steroidal anti-inflammatory drugs (NSAIDs) are the main choices for controlling inflammation. However, their adverse effects limit their clinical use. Sesame (Sesamum indicum L.) is one of the oldest cultivated plants in the world. Its extracts, such as sesame oil, have been widely used since ancient times. Recently, sesame oil and its lignan sesamol have been proved to be potent anti-inflammatory agents. They have an excellent protective effect against endotoxin-associated inflammatory damage because they inhibit the release of inflammatory mediators. Sesamol also inhibits endotoxins from binding to its receptor; this reduces inflammatory transcription factor NF-?B activation. In summary, sesame oil or sesamol may be beneficial for reducing the inflammatory response in inflammation-associated diseases.

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Hsu DZ, Chu PY, Liu MY. Sesame seed (sesamum indicum l.) extracts and their anti-inflammatory effect. In Emerging Trends in Dietary Components for Preventing and Combating Disease. American Chemical Society. 2012. p. 335-341. (ACS Symposium Series). https://doi.org/10.1021/bk-2012-1093.ch019