Severe cutaneous thrombosis with hemorrhagic necrosis in a patient with paroxysmal nocturnal hemoglobinuria: A case report and review of literature

Fu Nien Hsieh, Tsai-Yun Chen, Yu-Yun Lee

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Abstract

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, chronic acquired clonal stem cell disorder, typically manifesting hemolysis, pancytopenia and thrombosis in various organs. PNH-associated cutaneous thrombosis is extremely rare. Herein, we report a case of severe cutaneous thrombosis with hemorrhagic necrosis in a patient with PNH and review the literature.

Original languageEnglish
Pages (from-to)138-141
Number of pages4
JournalDermatologica Sinica
Volume35
Issue number3
DOIs
Publication statusPublished - 2017 Sep 1

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Paroxysmal Hemoglobinuria
Thrombosis
Necrosis
Skin
Pancytopenia
Hemolysis
Stem Cells

All Science Journal Classification (ASJC) codes

  • Dermatology

Cite this

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abstract = "Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, chronic acquired clonal stem cell disorder, typically manifesting hemolysis, pancytopenia and thrombosis in various organs. PNH-associated cutaneous thrombosis is extremely rare. Herein, we report a case of severe cutaneous thrombosis with hemorrhagic necrosis in a patient with PNH and review the literature.",
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