Shrimp white spot syndrome - From pathology to pathogenomics

Kuan Fu Liu, Wang Jing Liu, Guang Hsiung Kou, Chu Fang Lo

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)


For shrimp with low-level white spot syndrome virus (WSSV, = PRDV) infection, environmental or physiological stresses can trigger replication of the virus and lead to a full-blown outbreak of white spot disease. This review will describe how pathogenomic studies have revealed some of the mechanisms that underlie this aspect of WSSV pathology. In the model that emerges, stressors activate shrimp STAT (signal transducer and activator of transcription), which is then annexed by the virus and used to activate the promoter of the immediate early gene WSSV ie1. This in turn leads to rapid replication of the virus.

Original languageEnglish
Pages (from-to)55-58
Number of pages4
JournalFish Pathology
Issue number2
Publication statusPublished - 2009 Jun

All Science Journal Classification (ASJC) codes

  • Aquatic Science
  • Animal Science and Zoology


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