Significance of the V-type ATPase for the adaptation to stressful growth conditions and its regulation on the molecular and biochemical level

K. J. Dietz, N. Tavakoli, C. Kluge, T. Mimura, S. S. Sharma, G. C. Harris, A. N. Chardonnens, D. Golldack

Research output: Contribution to journalArticlepeer-review

269 Citations (Scopus)

Abstract

Two electrogenic H+-pumps, the vacuolar type H+-ATPase (V-ATPase) and the vacuolar pyrophosphatase, coexist at membranes of the secretory pathway of plants. The V-ATPase is the dominant H+-pump at endomembranes of most plant cells, both in terms of protein amount and, frequently, also in activity. The V-ATPase is indispensable for plant growth under normal conditions due to its role in energizing secondary transport, maintenance of solute homeostasis and, possibly, in facilitating vesicle fusion. Under stress conditions such as salinity, drought, cold, acid stress, anoxia, and excess heavy metals in the soil, survival of the cells depends strongly on maintaining or adjusting the activity of the V-ATPase. Regulation of gene expression and activity are involved in adapting the V-ATPase on long- and short-term bases. The mechanisms known to regulate the V-ATPase are summarized in this paper with an emphasis on their implications for growth and development under stress.

Original languageEnglish
Pages (from-to)1969-1980
Number of pages12
JournalJournal of experimental botany
Volume52
Issue number363
DOIs
Publication statusPublished - 2001

All Science Journal Classification (ASJC) codes

  • Physiology
  • Plant Science

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