Simple synthesis and functionalization of iron nanoparticles for magnetic resonance imaging

Soshan Cheong, Peter Ferguson, Kirk W. Feindel, Ian F. Hermans, Paul T. Callaghan, Claire Meyer, Angela Slocombe, Chia Hao Su, Fong Yu Cheng, Chen-Sheng Yeh, Bridget Ingham, Michael F. Toney, Richard D. Tilley

Research output: Contribution to journalArticle

106 Citations (Scopus)

Abstract

Visualizing small tumors: A novel, facile synthesis leads to the formation of strongly magnetic single-crystal core/shell iron/iron oxide nanoparticles without the use of highly toxic chemicals. The core/shell nanoparticles are highly effective MRI contrast agents and enable unambiguous detection of small tumors of 1-3 mm in vivo (see picture).

Original languageEnglish
Pages (from-to)4206-4209
Number of pages4
JournalAngewandte Chemie - International Edition
Volume50
Issue number18
DOIs
Publication statusPublished - 2011 Apr 26

Fingerprint

Magnetic resonance
Tumors
Iron
Nanoparticles
Imaging techniques
Poisons
Iron oxides
Magnetic resonance imaging
Contrast Media
Single crystals
ferric oxide

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)

Cite this

Cheong, S., Ferguson, P., Feindel, K. W., Hermans, I. F., Callaghan, P. T., Meyer, C., ... Tilley, R. D. (2011). Simple synthesis and functionalization of iron nanoparticles for magnetic resonance imaging. Angewandte Chemie - International Edition, 50(18), 4206-4209. https://doi.org/10.1002/anie.201100562
Cheong, Soshan ; Ferguson, Peter ; Feindel, Kirk W. ; Hermans, Ian F. ; Callaghan, Paul T. ; Meyer, Claire ; Slocombe, Angela ; Su, Chia Hao ; Cheng, Fong Yu ; Yeh, Chen-Sheng ; Ingham, Bridget ; Toney, Michael F. ; Tilley, Richard D. / Simple synthesis and functionalization of iron nanoparticles for magnetic resonance imaging. In: Angewandte Chemie - International Edition. 2011 ; Vol. 50, No. 18. pp. 4206-4209.
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Cheong, S, Ferguson, P, Feindel, KW, Hermans, IF, Callaghan, PT, Meyer, C, Slocombe, A, Su, CH, Cheng, FY, Yeh, C-S, Ingham, B, Toney, MF & Tilley, RD 2011, 'Simple synthesis and functionalization of iron nanoparticles for magnetic resonance imaging', Angewandte Chemie - International Edition, vol. 50, no. 18, pp. 4206-4209. https://doi.org/10.1002/anie.201100562

Simple synthesis and functionalization of iron nanoparticles for magnetic resonance imaging. / Cheong, Soshan; Ferguson, Peter; Feindel, Kirk W.; Hermans, Ian F.; Callaghan, Paul T.; Meyer, Claire; Slocombe, Angela; Su, Chia Hao; Cheng, Fong Yu; Yeh, Chen-Sheng; Ingham, Bridget; Toney, Michael F.; Tilley, Richard D.

In: Angewandte Chemie - International Edition, Vol. 50, No. 18, 26.04.2011, p. 4206-4209.

Research output: Contribution to journalArticle

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