Sinusoidal fetal heart rate pattern during chemotherapy in a pregnant women with acute myelogenous leukemia

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Abstract

A 22-year-old woman was referred to our hospital because of severe anemia in the 20th week of gestation. Acute myelogenous leukemia was diagnosed and she was treated with multiple-agent chemotherapy in the second and third trimester. Although the patient tolerated the intensive treatment, an intermittent sinusoidal fetal heart rate pattern was detected during chemotherapy. Complete remission was achieved at the 35th week of gestation. An underweight baby boy, suffering from pancytopenia, was delivered by cesarean section at 36 weeks' gestation. The baby recovered well and had adequate growth. No abnormalities were found at examination two months after birth. The fetal sinusoidal heart rate pattern may have been induced by severe anemia due to myelosuppression caused by the transplacental receipt of chemotherapeutic agents.

Original languageEnglish
Pages (from-to)562-565
Number of pages4
JournalJournal of the Formosan Medical Association
Volume94
Issue number9
Publication statusPublished - 1995 Jan 1

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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