Spatial heterogeneity of gut microbiota reveals multiple bacterial communities with distinct characteristics

Hsiao-Pei Lu, Yung Chih Lai, Shiao Wei Huang, Huang Chi Chen, Chih Hao Hsieh, Hon Tsen Yu

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

We analyzed bacterial communities of six distinct gut sites (the food bolus and mucus layer of the proximal small intestine, cecum and distal large intestine), using wild folivorous flying squirrels. We found significant spatial heterogeneity in composition, diversity, and species abundance distributions (SADs) of gut microbiota, corresponding to physicochemical conditions. High diversity was detected in the mucus layer of small intestine and the food bolus of cecum, followed by the food bolus of large intestine and the mucus layer of cecum, and relatively low diversity in the food bolus of small intestine and the mucus layer of large intestine, likely due to disturbance and resource partitioning. The SADs showed succession-like patterns in the food bolus communities from the proximal to distal gut. Notably, each mucus layer community had a unique pattern different from the food bolus community of the same compartment, with distinct relative abundances of dominant species. In combination with data from other mammalian fecal samples, we concluded that gut microbiota were apparently dynamic in community structure, from low species richness with unequal abundances to high species richness with equal abundances; these findings were interpreted as strong habitat effects on bacterial communities.

Original languageEnglish
Article number6185
JournalScientific reports
Volume4
DOIs
Publication statusPublished - 2014 Aug 26

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Mucus
Food
Cecum
Large Intestine
Small Intestine
Sciuridae
Ecosystem
Gastrointestinal Microbiome

All Science Journal Classification (ASJC) codes

  • General

Cite this

Lu, Hsiao-Pei ; Lai, Yung Chih ; Huang, Shiao Wei ; Chen, Huang Chi ; Hsieh, Chih Hao ; Yu, Hon Tsen. / Spatial heterogeneity of gut microbiota reveals multiple bacterial communities with distinct characteristics. In: Scientific reports. 2014 ; Vol. 4.
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Spatial heterogeneity of gut microbiota reveals multiple bacterial communities with distinct characteristics. / Lu, Hsiao-Pei; Lai, Yung Chih; Huang, Shiao Wei; Chen, Huang Chi; Hsieh, Chih Hao; Yu, Hon Tsen.

In: Scientific reports, Vol. 4, 6185, 26.08.2014.

Research output: Contribution to journalArticle

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