Stem cell transplantation therapy in Parkinson’s disease

Mu Hui Fu, Chia Ling Li, Hsiu Lien Lin, Pei Chun Chen, Marcus J. Calkins, Yu Fan Chang, Pei Hsun Cheng, Shang Hsun Yang

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19 Citations (Scopus)

Abstract

Ineffective therapeutic treatments and inadequate repair ability in the central nervous system are disturbing problems for several neurological diseases. Fortunately, the development of clinically applicable populations of stem cells has provided an avenue to overcome the failure of endogenous repair systems and substitute new cells into the damaged brain. However, there are still several existing obstacles to translating into clinical application. Here we review the stem-cell based therapies for Parkinson’s disease and discuss the potential advantages and drawbacks. We hope this review may provide suggestions for viable strategies to overcome the current technical and biological issues associated with the application of stem cells in Parkinson’s disease.

Original languageEnglish
Article number597
JournalSpringerPlus
Volume4
Issue number1
DOIs
Publication statusPublished - 2015 Dec 1

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All Science Journal Classification (ASJC) codes

  • General

Cite this

Fu, M. H., Li, C. L., Lin, H. L., Chen, P. C., Calkins, M. J., Chang, Y. F., Cheng, P. H., & Yang, S. H. (2015). Stem cell transplantation therapy in Parkinson’s disease. SpringerPlus, 4(1), [597]. https://doi.org/10.1186/s40064-015-1400-1