Stepwise gray-scale light-induced electric field gradient for passive and continuous separation of microparticles

I. Fang Cheng, Shing Lun Liu, Cheng Che Chung, Hsien-Chang Chang

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

This article presents a gray-scale light-induced dielectrophoresis (GS-LIDEP) method that induces the lateral displacements normal to the through-flow for continuous and passive separation of microparticles. In general, DEP force only can affect the particles within very local areas due to the electric field is exponentially decayed by the distance away from the electrodes. Unlike with conventional LIDEP, a broad-ranged electrical field gradient can easily be created by GS pattern illumination, which induces DEP forces with two directions for continuous separation of particles to their specific sub-channels. Candia albicans were effectively guided to the specific outlet with the efficiency of 90% to increase the concentration of the sample below the flow rate of 0.6 μl/min. 2 and 10 μm polystyrene particles can also be passively and well separated using the multi-step GS pattern through positive and negative DEP forces, respectively, under an applied voltage of 36 V p-p at the frequency of 10 kHz. GS-LIDEP generated a wide-ranged DEP force that is capable of working on the entire area of the microchannel, and thus the mix of particles can be passively and continuously separated toward the opposite directions by the both positive and negative GS-LIDEP forces. This simple, low cost, and flexible separation/manipulation platform could be very promising for many applications, such as in-field detections/pretreatments.

Original languageEnglish
Pages (from-to)95-105
Number of pages11
JournalMicrofluidics and Nanofluidics
Volume12
Issue number1-4
DOIs
Publication statusPublished - 2012 Jan 1

Fingerprint

gray scale
microparticles
Electrophoresis
Electric fields
gradients
electric fields
Microchannels
Polystyrenes
Lighting
Flow rate
outlets
microchannels
Electrodes
pretreatment
Electric potential
manipulators
polystyrene
platforms
flow velocity
illumination

All Science Journal Classification (ASJC) codes

  • Condensed Matter Physics
  • Electronic, Optical and Magnetic Materials
  • Materials Chemistry

Cite this

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title = "Stepwise gray-scale light-induced electric field gradient for passive and continuous separation of microparticles",
abstract = "This article presents a gray-scale light-induced dielectrophoresis (GS-LIDEP) method that induces the lateral displacements normal to the through-flow for continuous and passive separation of microparticles. In general, DEP force only can affect the particles within very local areas due to the electric field is exponentially decayed by the distance away from the electrodes. Unlike with conventional LIDEP, a broad-ranged electrical field gradient can easily be created by GS pattern illumination, which induces DEP forces with two directions for continuous separation of particles to their specific sub-channels. Candia albicans were effectively guided to the specific outlet with the efficiency of 90{\%} to increase the concentration of the sample below the flow rate of 0.6 μl/min. 2 and 10 μm polystyrene particles can also be passively and well separated using the multi-step GS pattern through positive and negative DEP forces, respectively, under an applied voltage of 36 V p-p at the frequency of 10 kHz. GS-LIDEP generated a wide-ranged DEP force that is capable of working on the entire area of the microchannel, and thus the mix of particles can be passively and continuously separated toward the opposite directions by the both positive and negative GS-LIDEP forces. This simple, low cost, and flexible separation/manipulation platform could be very promising for many applications, such as in-field detections/pretreatments.",
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Stepwise gray-scale light-induced electric field gradient for passive and continuous separation of microparticles. / Cheng, I. Fang; Liu, Shing Lun; Chung, Cheng Che; Chang, Hsien-Chang.

In: Microfluidics and Nanofluidics, Vol. 12, No. 1-4, 01.01.2012, p. 95-105.

Research output: Contribution to journalArticle

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